Effectiveness of Individualized Homoeopathic Medicines in Acrophobia: A Randomized Single-blind Controlled Trial

-treatmentAQ scale scores. Independent t-test (Welch’s) was applied between the two groups to compare the mean difference in scores and assess the overall effectiveness of homoeopathic treatment compared to placebo. Effect size (Cohen’s d) was calculated to determine the magnitude of treatment effect between the groups. Data were expressed as mean ± standard deviation (SD). A p-value of less than 0.05 (p < 0.05) was considered statistically significant. Results:. 125 screened patients, 90 were enrolled and randomly allocated equally into a medicinal group (n=45) and a placebo group (n=45). Acrophobia was most prevalent among patients aged 36–45 years (33.3%), with a slight female predominance (57.8%). Most participants had a symptom duration of 1–5 years (45.6%) and belonged to the middle socioeconomic group (55.6%). The medicinal group demonstrated a highly significant reduction in Acrophobia Questionnaire (AQ) scores after one year of treatment (p<0.001), in compare to the placebo group . Sulphur was the most frequently prescribed remedy, followed by Argentum nitricum and other individualized remedies. These findings indicate significant improvement in acrophobia symptoms following individualized homoeopathic treatment compared with placebo. Conclusion: The findings suggest that individualized homoeopathic medicines are significantly effective than placebo in reducing the intensity of acrophobia and improving overall well-being as measured by AQ Scores. Homoeopathic intervention demonstrated both statistical and clinical benefits, highlighting its potential as an effective complementary therapeutic approach in acrophobia management. Keywords: Acrophobia; Homoeopathy; Individualized Medicines; Acrophobia Questionnaire; Placebo; Randomized Controlled Trial; Specific Phobia.