Adolescent pemphigus vulgaris: A diagnostic dilemma

Pemphigus vulgaris is a rare autoimmune bullous disorder in adolescents and is frequently misdiagnosed in its early stages. We report the case of a 14-year-old girl who presented with multiple flaccid bullae associated with oral erosions. The diagnosis of adolescent pemphigus vulgaris was confirmed based on histopathological findings and direct immunofluorescence studies. The patient is currently on dexamethasone-azathioprine pulse therapy with a good clinical response. This case highlights the importance of early recognition and appropriate clinicopathological correlation in diagnosing this condition in the adolescent age group.

Authors

Institutions

Publication Details

Journal
Journal of Skin and Sexually Transmitted Diseases
Published
2026-10-31
DOI
https://doi.org/10.25259/jsstd_54_2026
Primary Topic
Autoimmune Bullous Skin Diseases
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Adolescent pemphigus vulgaris: A diagnostic dilemma

Rebecca Mathews, Balachandran Parapattu Kunjukunju, Thankappan Thonduparampil Pappen, Lina Varghese Varghese
Journal of Skin and Sexually Transmitted Diseases
Autoimmune Bullous Skin Diseases
article

Adolescent pemphigus vulgaris: A diagnostic dilemma

Rebecca Mathews, Balachandran Parapattu Kunjukunju, Thankappan Thonduparampil Pappen, Lina Varghese Varghese
article en

Abstract

Pemphigus vulgaris is a rare autoimmune bullous disorder in adolescents and is frequently misdiagnosed in its early stages. We report the case of a 14-year-old girl who presented with multiple flaccid bullae associated with oral erosions. The diagnosis of adolescent pemphigus vulgaris was confirmed based on histopathological findings and direct immunofluorescence studies. The patient is currently on dexamethasone-azathioprine pulse therapy with a good clinical response. This case highlights the importance of early recognition and appropriate clinicopathological correlation in diagnosing this condition in the adolescent age group.

Journal of Skin and Sexually Transmitted DiseasesVol. 0
Pushpagiri Medical College (IN)
Openalex Percentile: Top 12%
Autoimmune Bullous Skin Diseases
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Laika access coming soon