"Exosome Based Drug Delivery System:Recent Developments, Applications and Future Perspectives"

Exosome-based drug delivery systems have gained considerable attention in recent years due to their potential to improve the delivery of therapeutic agents. Exosomes are small extracellular vesicles released by cells that carry various biological molecules, including proteins, lipids, and nucleic acids. Their natural ability to interact with recipient cells makes them promising carriers for delivering drugs to specific tissues. Recent research has explored their applications in cancer therapy, neurological disorders, gene delivery, and regenerative medicine. Exosomes can transport different therapeutic agents, such as small-molecule drugs, proteins, and RNA-based therapeutics. Furthermore, advances in exosome engineering and drug-loading techniques have created new opportunities to improve targeting and therapeutic effectiveness. However, challenges related to isolation, purification, large-scale production, stability, and safety remain significant barriers to clinical application. This review summarizes recent developments in exosome-based drug delivery, highlights their potential advantages and limitations, and discusses future research directions for translating these promising nanocarriers into effective therapeutic approaches.