Reporting and interpretation in a hydrodissection trial: technical commentary on Bose et al. (2026)

Independent technical commentary on Bose et al. (Radiology, 2026; DOI 10.1148/radiol.260185). The note documents internal reporting discrepancies with precise PDF locations and separates these from statistical questions requiring original model output. It discusses the covariance specification for bilateral wrists and repeated observations, the unit used in the power calculation, and interpretation of nonsignificant treatment comparisons. No raw-data reanalysis was performed, and the commentary does not establish that the treatment findings are invalid. OpenAI ChatGPT assisted source checking, statistical interpretation, language editing, and preparation of the text; responsibility rests with the named author.