Acute fulminant Clostridium-Perfrigens sepsis with massive intravascular hemolysis in a young woman with sickle cell disease. Case presentation and review of the literature
To the Editor Sickle cell disease (SCD) is an inherited hemoglobinopathy caused by a single amino acid substitution at the sixth residue of the beta (β)-globin subunit (p.Glu6Val) Vaso-occlusion, hemolytic anemia and vasculopathy are the hallmarks of SCD pathophysiology, leading to high morbility and mortality.
Authors
- LAURA ELENA MAFFEI
- Beatrice Basso
- Mauro Polzoni (ORCID: https://orcid.org/0000-0003-2559-8670)
- Maria Ilaria Del Principe (ORCID: https://orcid.org/0000-0002-3958-0669)
- Nicolina Rita Ardu
- Lorenza Torti (ORCID: https://orcid.org/0000-0002-1736-5570)
Publication Details
- Journal
- Mediterranean Journal of Hematology and Infectious Diseases
- Published
- 2026-10-31
- DOI
- https://doi.org/10.4084/mjhid.2026.080
- Primary Topic
- Hemoglobinopathies and Related Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00