High Expression of ACKR4 in Thymic Epithelial Progenitors of Adult Mice
High ACKR4-expressing cells located in the subcapsular zone and around pericytes at the corticomedullary junction express thymic epithelial cell (TEC) progenitor markers. During cortical TEC regeneration in adult mice, ACKR4 expression is upregulated in cells expressing the transcription factors p63 and Foxn1. Our findings suggest that ACKR4 is preferentially expressed in thymic epithelial progenitors in adult mice.
Authors
- Maryna Samus (ORCID: https://orcid.org/0000-0002-5397-2183)
- Shigeo Murata (ORCID: https://orcid.org/0000-0002-3177-3503)
- Antal Rot (ORCID: https://orcid.org/0000-0002-9730-6166)
- Christina Gkantsinikoudi (ORCID: https://orcid.org/0009-0005-7000-9953)
- Stefan Russo (ORCID: https://orcid.org/0000-0002-2234-5515)
- Neil Dufton (ORCID: https://orcid.org/0000-0002-6283-9210)
- Elin Hub
- Chikako Odaka (ORCID: https://orcid.org/0009-0004-1728-9987)
Institutions
- Queen Mary University of London (GB)
- William Harvey Research Institute (GB)
- The University of Tokyo (JP)
Publication Details
- Journal
- European Journal of Immunology
- Published
- 2026-10-30
- DOI
- https://doi.org/10.1002/eji.70305
- Primary Topic
- T-cell and B-cell Immunology
- Type
- article
- Field-Weighted Citation Impact
- 0.00