I23j. OPERATIONAL MATHEMATICS OF HNU, RRR AND nAV

HNU is specified as a dimensionless domain-specific measure of conformity with a pre-established region of normality. RRR is the boundary of a continuous range of amplitudes of a subsequent intervention satisfying prespecified safety, recovery and functional criteria. RRR_ref provides a reference scale and nAV is the ratio of the reserve to that reference. Interval trials, censoring, uncertainty, numerical examples and an analytical RC model are examined. Cross-domain transferability and predictive value remain testable hypotheses. Keywords: Vitology; viability; HNU; RRR; nAV; reference reserve; uncertainty; cross-domain transferability.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-10-31
DOI
https://doi.org/10.5281/zenodo.23846529
Primary Topic
Statistical Methods in Clinical Trials
Type
preprint
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preprint

I23j. OPERATIONAL MATHEMATICS OF HNU, RRR AND nAV

Serhii Hostiunin
Zenodo (CERN European Organization for Nuclear Research)
Statistical Methods in Clinical Trials
preprint

I23j. OPERATIONAL MATHEMATICS OF HNU, RRR AND nAV

Serhii Hostiunin
preprint en

Abstract

HNU is specified as a dimensionless domain-specific measure of conformity with a pre-established region of normality. RRR is the boundary of a continuous range of amplitudes of a subsequent intervention satisfying prespecified safety, recovery and functional criteria. RRR_ref provides a reference scale and nAV is the ratio of the reserve to that reference. Interval trials, censoring, uncertainty, numerical examples and an analytical RC model are examined. Cross-domain transferability and predictive value remain testable hypotheses. Keywords: Vitology; viability; HNU; RRR; nAV; reference reserve; uncertainty; cross-domain transferability.

Zenodo (CERN European Organization for Nuclear Research)
Statistical Methods in Clinical Trials
DOIOpen Access PDFOpenAlex
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I23j. OPERATIONAL MATHEMATICS OF HNU, RRR AND nAV — Serhii Hostiunin · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS