Additional file 1 of Quantification of NLRP3–caspase-1 complex assembly reveals a non-linear association with 30-day mortality in sepsis: a proof-of-concept pilot study
Additional file 1: Flow diagram illustrating patient screening, eligibility assessment, study inclusion, and allocation into NLRP3 inflammasome activity groups. A total of 121 patients were screened, of whom 80 met the inclusion criteria and 78 were included in the final analysis. Patients were subsequently stratified according to NLRP3 inflammasome activity into low (n = 28), intermediate (n = 23), and high activity groups (n = 27).
Authors
- Birte Dyck (ORCID: https://orcid.org/0000-0002-1013-0015)
- Tim Rahmel (ORCID: https://orcid.org/0000-0002-7039-6288)
- Christian Putensen (ORCID: https://orcid.org/0000-0003-1599-9809)
- Lars Bergmann (ORCID: https://orcid.org/0000-0002-8603-8549)
- Björn Koos (ORCID: https://orcid.org/0000-0002-0544-4124)
- Andrea Witowski (ORCID: https://orcid.org/0009-0000-6522-832X)
- Katharina Rump (ORCID: https://orcid.org/0000-0003-2220-519X)
- Michael Adamzik (ORCID: https://orcid.org/0000-0002-7188-4873)
- Patrick Thon (ORCID: https://orcid.org/0009-0000-0573-3893)
- Fabian Mehl (ORCID: https://orcid.org/0000-0002-3357-7143)
- Willy Junior Chedjou
- Dietrich Henzler
Institutions
- University Hospital Bonn (DE)
- Ruhr University Bochum (DE)
Publication Details
- Journal
- Figshare
- Published
- 2026-10-29
- DOI
- https://doi.org/10.6084/m9.figshare.34864412
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00