Tumour-anchored Purkinje-mediated ventricular tachycardia in a child with cardiac rhabdomyoma

Cardiac rhabdomyomas are associated with ventricular arrhythmias, but mechanisms remain uncertain. A 10-year-old boy with tuberous sclerosis complex developed verapamil-sensitive fascicular ventricular tachycardia adjacent to a residual cardiac rhabdomyoma. Electrophysiological mapping demonstrated Purkinje-mediated reentry. Catheter ablation at a tumour-adjacent site eliminated the arrhythmia, suggesting that residual rhabdomyoma may anchor a localised reentrant substrate.

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Publication Details

Journal
Cardiology in the Young
Published
2026-10-30
DOI
https://doi.org/10.1017/s1047951126124779
Primary Topic
Cardiac Arrhythmias and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Tumour-anchored Purkinje-mediated ventricular tachycardia in a child with cardiac rhabdomyoma

Gaku Izumi, Taro Temma, Daisuke Sasaki
Cardiology in the Young
Cardiac Arrhythmias and Treatments
article

Tumour-anchored Purkinje-mediated ventricular tachycardia in a child with cardiac rhabdomyoma

Gaku Izumi, Taro Temma, Daisuke Sasaki
article en

Abstract

Cardiac rhabdomyomas are associated with ventricular arrhythmias, but mechanisms remain uncertain. A 10-year-old boy with tuberous sclerosis complex developed verapamil-sensitive fascicular ventricular tachycardia adjacent to a residual cardiac rhabdomyoma. Electrophysiological mapping demonstrated Purkinje-mediated reentry. Catheter ablation at a tumour-adjacent site eliminated the arrhythmia, suggesting that residual rhabdomyoma may anchor a localised reentrant substrate.

Cardiology in the Young
Hokkaido University (JP), Sakakibara Hospital (JP)
Good health and well-being
Openalex Percentile: Top 11%
Cardiac Arrhythmias and Treatments
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