ENDOCATOR AND ATP BIOLUMINESCENCE TECHNOLOGY: A NOVEL PARADIGM FOR OBJECTIVE ASSESSMENT OF ROOT CANAL DISINFECTION – A REVIEW ARTICLE

The success of endodontic treatment depends largely on the effective elimination of microorganisms, necrotic tissue remnants, and organic debris from the root canal system. Despite significant advances in instrumentation and irrigation protocols, clinicians still lack an objective chairside method to verify canal cleanliness before obturation. Currently available assessment techniques, including microbial culture, polymerase chain reaction, and microscopic analysis, are predominantly research-based tools and are not routinely applicable in clinical practice. Recently, ATP bioluminescence technology has emerged as a promising method for rapid assessment of residual biological contamination within root canals.[1,10,11] Endocator is a novel ATP-based chairside diagnostic system that measures ATP-related bioluminescence signals to quantify residual biological material and generate an objective cleanliness score.[1,5] This narrative review discusses the biological basis of ATP bioluminescence, the operating principle of Endocator, currently available laboratory and clinical evidence, potential applications in endodontic practice, advantages, limitations, and future directions.[1-5] Current evidence suggests that ATP-based assessment may enhance clinical decision-making by providing an objective measure of root canal cleanliness before obturation.[1]

Authors

Publication Details

Journal
European Journal Pharmaceutical and Medical Research
Published
2026-11-01
DOI
https://doi.org/10.5281/zenodo.23799276
Primary Topic
Endodontics and Root Canal Treatments
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

ENDOCATOR AND ATP BIOLUMINESCENCE TECHNOLOGY: A NOVEL PARADIGM FOR OBJECTIVE ASSESSMENT OF ROOT CANAL DISINFECTION – A REVIEW ARTICLE

Dr. Sahadev Chickmagaravalli Krishnegowda, Dr. Sandeep Rudranaik, Dr. Bharath M. J., Dr. Raghu Kachenahalli Narasimhaiah, Dr. Rakshith Jayanna, Dr. Likitha Venkatesh*
3 links
European Journal Pharmaceutical and Medical Research
Endodontics and Root Canal Treatments
article

ENDOCATOR AND ATP BIOLUMINESCENCE TECHNOLOGY: A NOVEL PARADIGM FOR OBJECTIVE ASSESSMENT OF ROOT CANAL DISINFECTION – A REVIEW ARTICLE

Dr. Sahadev Chickmagaravalli Krishnegowda, Dr. Sandeep Rudranaik, Dr. Bharath M. J., Dr. Raghu Kachenahalli Narasimhaiah, Dr. Rakshith Jayanna, Dr. Likitha Venkatesh*
article en

Abstract

The success of endodontic treatment depends largely on the effective elimination of microorganisms, necrotic tissue remnants, and organic debris from the root canal system. Despite significant advances in instrumentation and irrigation protocols, clinicians still lack an objective chairside method to verify canal cleanliness before obturation. Currently available assessment techniques, including microbial culture, polymerase chain reaction, and microscopic analysis, are predominantly research-based tools and are not routinely applicable in clinical practice. Recently, ATP bioluminescence technology has emerged as a promising method for rapid assessment of residual biological contamination within root canals.[1,10,11] Endocator is a novel ATP-based chairside diagnostic system that measures ATP-related bioluminescence signals to quantify residual biological material and generate an objective cleanliness score.[1,5] This narrative review discusses the biological basis of ATP bioluminescence, the operating principle of Endocator, currently available laboratory and clinical evidence, potential applications in endodontic practice, advantages, limitations, and future directions.[1-5] Current evidence suggests that ATP-based assessment may enhance clinical decision-making by providing an objective measure of root canal cleanliness before obturation.[1]

European Journal Pharmaceutical and Medical Research
Good health and well-being
Openalex Percentile: Top 10%
Endodontics and Root Canal Treatments
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Laika access coming soon