Beyond fatigue: optimising cardiac compression efficacy for the asphyxiated newborn

Chest compressions are among the rarest interventions performed during neonatal resuscitation, required in fewer than 0.1% of births. 1 Effective resuscitation, including chest compressions, is crucial in reducing morbidity and mortality in these infants. 2 , 3 Assessing compression quality and its relationship to meaningful clinical outcomes has proven challenging. Much of the available evidence continues to rely on simulation or animal models rather than clinical studies. Unlike adult resuscitation, where devices are available to provide consistent chest compressions with machine precision, 4 neonatal resuscitation relies solely on clinicians. Previous neonatal manikin studies have similarly demonstrated deterioration in compression performance with prolonged resuscitation. 5 For human performance to emulate a machine-like consistency, human factors such as fatigue need to be managed.

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Publication Details

Journal
Pediatric Research
Published
2026-10-30
DOI
https://doi.org/10.1038/s41390-026-05634-9
Primary Topic
Cardiac Arrest and Resuscitation
Type
article
Field-Weighted Citation Impact
0.00

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article

Beyond fatigue: optimising cardiac compression efficacy for the asphyxiated newborn

Uditha Kariyawasam, Atul Malhotra
Pediatric Research
Cardiac Arrest and Resuscitation
article

Beyond fatigue: optimising cardiac compression efficacy for the asphyxiated newborn

Uditha Kariyawasam, Atul Malhotra
article en

Abstract

Chest compressions are among the rarest interventions performed during neonatal resuscitation, required in fewer than 0.1% of births. 1 Effective resuscitation, including chest compressions, is crucial in reducing morbidity and mortality in these infants. 2 , 3 Assessing compression quality and its relationship to meaningful clinical outcomes has proven challenging. Much of the available evidence continues to rely on simulation or animal models rather than clinical studies. Unlike adult resuscitation, where devices are available to provide consistent chest compressions with machine precision, 4 neonatal resuscitation relies solely on clinicians. Previous neonatal manikin studies have similarly demonstrated deterioration in compression performance with prolonged resuscitation. 5 For human performance to emulate a machine-like consistency, human factors such as fatigue need to be managed.

Pediatric Research
Hudson Institute of Medical Research (AU), Monash Children’s Hospital (AU), Monash Health (AU), Monash University (AU)
Cerebral Palsy Alliance, National Health and Medical Research Council
Good health and well-being
Openalex Percentile: Top 10%
Cardiac Arrest and Resuscitation
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