Case Report: Late postpartum eclampsia-associated reversible posterior encephalopathy syndrome with anti-DPPX encephalitis

Posterior reversible encephalopathy syndrome (PRES) is a clinical-radiological syndrome characterized by headaches, seizures, visual disturbances, and focal neurological deficits, accompanied by specific cranial imaging findings. Common triggers of PRES include hypertension/eclampsia, renal disease, autoimmune disorders, and drug abuse. PRES associated with autoimmune encephalitis is a rare phenomenon that presents diagnostic challenges in clinical settings, often leading to missed diagnosis and delayed treatment. We report a case involving a patient with late-onset eclampsia, occurring 26 days after cesarean section, who exhibited dual neurological syndromes of reversible posterior encephalopathy syndrome and anti-DPPX encephalitis. MRI resonance imaging revealed vasogenic cerebral edema and extensive enhancing lesions.

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Journal
Frontiers in Immunology
Published
2026-10-30
DOI
https://doi.org/10.3389/fimmu.2026.1967757
Primary Topic
Neurological Complications and Syndromes
Type
article
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Case Report: Late postpartum eclampsia-associated reversible posterior encephalopathy syndrome with anti-DPPX encephalitis

Yuyan He, Liumei Ma, Linming Zhang, Xuanlin Xing
3 links
Frontiers in Immunology
Neurological Complications and Syndromes
article

Case Report: Late postpartum eclampsia-associated reversible posterior encephalopathy syndrome with anti-DPPX encephalitis

Yuyan He, Liumei Ma, Linming Zhang, Xuanlin Xing
article en

Abstract

Posterior reversible encephalopathy syndrome (PRES) is a clinical-radiological syndrome characterized by headaches, seizures, visual disturbances, and focal neurological deficits, accompanied by specific cranial imaging findings. Common triggers of PRES include hypertension/eclampsia, renal disease, autoimmune disorders, and drug abuse. PRES associated with autoimmune encephalitis is a rare phenomenon that presents diagnostic challenges in clinical settings, often leading to missed diagnosis and delayed treatment. We report a case involving a patient with late-onset eclampsia, occurring 26 days after cesarean section, who exhibited dual neurological syndromes of reversible posterior encephalopathy syndrome and anti-DPPX encephalitis. MRI resonance imaging revealed vasogenic cerebral edema and extensive enhancing lesions.

Frontiers in ImmunologyVol. 17
First Affiliated Hospital of Kunming Medical University (CN)
Good health and well-being
Openalex Percentile: Top 12%
Neurological Complications and Syndromes
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Case Report: Late postpartum eclampsia-associated reversible posterior encephalopathy syndrome with anti-DPPX encephalitis — Yuyan He, Liumei Ma, et al. · Frontiers in Immunology (2026) | TGRS Research Map | TGRS