Contemporary applications of echocardiography in the diagnosis and management of hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is an inherited form of cardiomyopathy characterized predominantly by asymmetric myocardial hypertrophy. The condition demonstrates substantial clinical heterogeneity and is associated with an increased risk of adverse outcomes, including heart failure, cardiac arrhythmias, and sudden cardiac death. Accurate diagnosis and comprehensive management are therefore critical for optimizing clinical outcomes in affected individuals. Echocardiography, owing to its noninvasive nature, wide availability, and capacity for real-time assessment, serves as a central imaging modality in the diagnostic evaluation and management continuum of HCM. Recent developments in echocardiographic technology, including conventional modalities, speckle tracking imaging, three-dimensional echocardiography, and contrast-enhanced echocardiography, have expanded the role of this technique in disease detection, phenotypic classification, functional assessment, prognostic stratification, and therapeutic decision-making. This review summarizes current advances in echocardiographic applications in HCM and highlights their clinical utility in supporting optimized diagnostic and management strategies.

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Publication Details

Journal
Journal of Cardiothoracic Surgery
Published
2026-10-30
DOI
https://doi.org/10.1186/s13019-026-04780-9
Primary Topic
Cardiomyopathy and Myosin Studies
Type
article
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article

Contemporary applications of echocardiography in the diagnosis and management of hypertrophic cardiomyopathy

Mei Zhu, Zheng Ronghui
1 links
Journal of Cardiothoracic Surgery
Cardiomyopathy and Myosin Studies
article

Contemporary applications of echocardiography in the diagnosis and management of hypertrophic cardiomyopathy

Mei Zhu, Zheng Ronghui
article en

Abstract

Hypertrophic cardiomyopathy (HCM) is an inherited form of cardiomyopathy characterized predominantly by asymmetric myocardial hypertrophy. The condition demonstrates substantial clinical heterogeneity and is associated with an increased risk of adverse outcomes, including heart failure, cardiac arrhythmias, and sudden cardiac death. Accurate diagnosis and comprehensive management are therefore critical for optimizing clinical outcomes in affected individuals. Echocardiography, owing to its noninvasive nature, wide availability, and capacity for real-time assessment, serves as a central imaging modality in the diagnostic evaluation and management continuum of HCM. Recent developments in echocardiographic technology, including conventional modalities, speckle tracking imaging, three-dimensional echocardiography, and contrast-enhanced echocardiography, have expanded the role of this technique in disease detection, phenotypic classification, functional assessment, prognostic stratification, and therapeutic decision-making. This review summarizes current advances in echocardiographic applications in HCM and highlights their clinical utility in supporting optimized diagnostic and management strategies.

Journal of Cardiothoracic Surgery
Shandong Provincial Hospital (CN), Shandong First Medical University (CN)
Good health and well-being
Openalex Percentile: Top 11%
Cardiomyopathy and Myosin Studies
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Contemporary applications of echocardiography in the diagnosis and management of hypertrophic cardiomyopathy — Mei Zhu, Zheng Ronghui · Journal of Cardiothoracic Surgery (2026) | TGRS Research Map | TGRS