The Guangzhou Model of Peritoneal Dialysis Care: A Scalable Hub-and-Satellite Network

Chronic kidney disease and end-stage renal disease pose growing challenges to health systems worldwide, particularly in settings where access to high-quality peritoneal dialysis (PD) services remains variable. In response to persistent gaps in primary care-level quality control in China, this study evaluated the implementation of the Guangzhou model, a hub-and-satellite collaborative PD network led by the First Affiliated Hospital of Sun Yat-sen University, with a focus on its impact on service accessibility and long-term clinical outcomes. Using a multicenter retrospective cohort design, the authors examined network expansion across 122 satellite centers and evaluated clinical outcomes in a subset of 15 representative centers with stable longitudinal follow-up data. Survival outcomes among patients treated between 2015 and 2025 were analyzed using Kaplan-Meier methods and compared with national reference standards. Network expansion was associated with substantial improvements in patient retention and a marked increase in dialysis duration. Under a standardized management and training framework, satellite centers within Guangdong Province achieved survival and complication control outcomes that approached those of the central hub. Long-term clinical outcomes at these centers were generally better than national averages, suggesting that care quality was maintained despite rapid scale-up. Overall, the Guangzhou model suggests that standardized training, continuous quality improvement, and digital support can facilitate the large-scale decentralization of high-quality PD services, offering a practical and scalable approach to addressing inequities in access to renal replacement therapy.

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Publication Details

Journal
NEJM Catalyst
Published
2026-10-30
DOI
https://doi.org/10.1056/cat.26.0209
Primary Topic
Dialysis and Renal Disease Management
Type
article
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article

The Guangzhou Model of Peritoneal Dialysis Care: A Scalable Hub-and-Satellite Network

Chunyan Yi, You Wu, Haiping Mao, Hongjian Ye et al.
NEJM Catalyst
Dialysis and Renal Disease Management
article

The Guangzhou Model of Peritoneal Dialysis Care: A Scalable Hub-and-Satellite Network

Chunyan Yi, You Wu, Haiping Mao, Hongjian Ye, Yinting Zheng, Wei Chen, Xiao Yang
article en

Abstract

Chronic kidney disease and end-stage renal disease pose growing challenges to health systems worldwide, particularly in settings where access to high-quality peritoneal dialysis (PD) services remains variable. In response to persistent gaps in primary care-level quality control in China, this study evaluated the implementation of the Guangzhou model, a hub-and-satellite collaborative PD network led by the First Affiliated Hospital of Sun Yat-sen University, with a focus on its impact on service accessibility and long-term clinical outcomes. Using a multicenter retrospective cohort design, the authors examined network expansion across 122 satellite centers and evaluated clinical outcomes in a subset of 15 representative centers with stable longitudinal follow-up data. Survival outcomes among patients treated between 2015 and 2025 were analyzed using Kaplan-Meier methods and compared with national reference standards. Network expansion was associated with substantial improvements in patient retention and a marked increase in dialysis duration. Under a standardized management and training framework, satellite centers within Guangdong Province achieved survival and complication control outcomes that approached those of the central hub. Long-term clinical outcomes at these centers were generally better than national averages, suggesting that care quality was maintained despite rapid scale-up. Overall, the Guangzhou model suggests that standardized training, continuous quality improvement, and digital support can facilitate the large-scale decentralization of high-quality PD services, offering a practical and scalable approach to addressing inequities in access to renal replacement therapy.

NEJM CatalystVol. 7(s1)
Sun Yat-sen University (CN), The First Affiliated Hospital, Sun Yat-sen University (CN), Tsinghua University (CN)
Good health and well-being
Openalex Percentile: Top 12%
Dialysis and Renal Disease Management
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