BRACHIO: Broad Representations Across Centres for Head-and-neck Imaging Oncology (HECKTOR 2026)

The HECKTOR 2026 challenge benchmarks machine learning for head and neck cancer, where teams delineate primary and nodal tumour volumes, perform TN staging, and predict recurrence-free survival (RFS). This report describes the submissions for the HECKTOR challenge of team nucli. As the three tasks span both dense and global information from multicentric PET/CT scans, we utilise self-supervised pre-trained encoders, training a 2D DINOv2 encoder (PET-DINOv2-MIPs) on HECKTOR 2026's PET scans. Our final test submission ensembles a DynUNet trained from scratch with a SwinUNETR whose Swin trunk was initialised from a SimMIM-pre-trained checkpoint for segmentation, reaching a mean Dice of 0.5409. For TN staging, GTVp/GTVn geometric features from the segmentation masks are fit to stage probabilities by logistic regression (LR) and fused with PET-DINOv2-MIPs deep features (PCA + LR) via a second-level LR, reaching balanced accuracies of 0.3962 (T-stage) and 0.6432 (N-stage). For the RFS prognosis task, we fine-tune the last two blocks of the PET-DINOv2-MIPs ViT-S encoder jointly with an MLP head under a CoxPH loss, concatenating clinical covariates with the imaging features, reaching a test Harrell's C-index of 0.6577 and a weighted challenge score of 0.5802. The prognosis result is comparable to the best entry of the previous edition and consistent with our internal cross-validation, while our segmentation result is well below it and limits the staging results that depend on it.

Authors

Publication Details

Journal
arXiv (Cornell University)
Published
2026-10-29
DOI
https://doi.org/10.48550/arxiv.2610.40068
Primary Topic
Medical Image Segmentation Techniques
Type
preprint
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preprint

BRACHIO: Broad Representations Across Centres for Head-and-neck Imaging Oncology (HECKTOR 2026)

Ine Dirks, Simon DeKeyser, Jef Vandemeulebroucke, Vicky De Ridder et al.
arXiv (Cornell University)
Medical Image Segmentation Techniques
preprint

BRACHIO: Broad Representations Across Centres for Head-and-neck Imaging Oncology (HECKTOR 2026)

Ine Dirks, Simon DeKeyser, Jef Vandemeulebroucke, Vicky De Ridder, Yannick Brackenier, Roxanne De Maeyer
preprint en

Abstract

The HECKTOR 2026 challenge benchmarks machine learning for head and neck cancer, where teams delineate primary and nodal tumour volumes, perform TN staging, and predict recurrence-free survival (RFS). This report describes the submissions for the HECKTOR challenge of team nucli. As the three tasks span both dense and global information from multicentric PET/CT scans, we utilise self-supervised pre-trained encoders, training a 2D DINOv2 encoder (PET-DINOv2-MIPs) on HECKTOR 2026's PET scans. Our final test submission ensembles a DynUNet trained from scratch with a SwinUNETR whose Swin trunk was initialised from a SimMIM-pre-trained checkpoint for segmentation, reaching a mean Dice of 0.5409. For TN staging, GTVp/GTVn geometric features from the segmentation masks are fit to stage probabilities by logistic regression (LR) and fused with PET-DINOv2-MIPs deep features (PCA + LR) via a second-level LR, reaching balanced accuracies of 0.3962 (T-stage) and 0.6432 (N-stage). For the RFS prognosis task, we fine-tune the last two blocks of the PET-DINOv2-MIPs ViT-S encoder jointly with an MLP head under a CoxPH loss, concatenating clinical covariates with the imaging features, reaching a test Harrell's C-index of 0.6577 and a weighted challenge score of 0.5802. The prognosis result is comparable to the best entry of the previous edition and consistent with our internal cross-validation, while our segmentation result is well below it and limits the staging results that depend on it.

arXiv (Cornell University)
Medical Image Segmentation Techniques
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