Comprehensive evaluation of large language models for pediatric pectus excavatum education

Background Large language models (LLMs) are increasingly used by patients and caregivers to find health information. However, their performance in providing Simplified Chinese education on pediatric pectus excavatum (PE) remains uncertain. This study comprehensively evaluated the responses generated by five mainstream LLMs. Methods Thirty PE-related frequently asked questions (FAQs) spanning five clinical domains were collected and submitted in Simplified Chinese to ChatGPT, Claude, DeepSeek, Qwen, and Kimi. Responses were evaluated by pediatric thoracic surgeons from three institutions for accuracy, completeness, and relevance, using a 6-point Likert scale. Readability was assessed using AlphaReadabilityChinese (ARC) 2.0 and the Chinese Readability Index Explorer (CRIE) 3.0. Understandability, actionability, and overall quality were evaluated with the Chinese Patient Education Materials Assessment Tool for Printable Materials (C-PEMAT-P) and the Global Quality Score (GQS). Friedman tests compared the models, followed by Holm-adjusted Wilcoxon signed-rank tests. Results All models achieved mean accuracy, completeness, and relevance scores above 4.9 on the 6-point scale, but the leading model differed by dimension. Claude had the highest mean accuracy (5.39 ± 0.28), completeness (5.22 ± 0.22), and GQS (4.80 ± 0.41), while DeepSeek had the highest relevance (5.42 ± 0.27). Qwen was the least readable: its median CRIE grade was 7.0, compared with 5.5 to 6.0 for the other models. Only 23.3% of its responses were at Grades 1–6, compared with 66.7–86.7% for the others. Overall C-PEMAT-P scores also differed ( p = 0.003), with Kimi showing the highest numerical mean total (12.17 ± 0.75). Qwen combined the highest actionability (2.57 ± 0.50) with the lowest understandability (9.47 ± 0.57) and GQS (3.10 ± 0.71). Conclusion Leading LLMs generally provided accurate, complete, and relevant Simplified Chinese answers to common pediatric PE questions, but no model performed best on every dimensions. LLM outputs should therefore be regarded as a supervised educational aid that require expert verification and adaptation to the health literacy of the intended audience, rather than as substitutes for specialist counseling.

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Publication Details

Journal
Frontiers in Public Health
Published
2026-10-30
DOI
https://doi.org/10.3389/fpubh.2026.1990753
Primary Topic
Artificial Intelligence in Healthcare and Education
Type
article
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article

Comprehensive evaluation of large language models for pediatric pectus excavatum education

Linhao Peng, Qiang Tang, Haifa Hong, Tao-Hsing Chang et al.
7 links
Frontiers in Public Health
Artificial Intelligence in Healthcare and Education
article

Comprehensive evaluation of large language models for pediatric pectus excavatum education

Linhao Peng, Qiang Tang, Haifa Hong, Tao-Hsing Chang, Hou-Chiang Tseng, Xiaolong Chen, Jing Xiong, Hao Shi
article en

Abstract

Background Large language models (LLMs) are increasingly used by patients and caregivers to find health information. However, their performance in providing Simplified Chinese education on pediatric pectus excavatum (PE) remains uncertain. This study comprehensively evaluated the responses generated by five mainstream LLMs. Methods Thirty PE-related frequently asked questions (FAQs) spanning five clinical domains were collected and submitted in Simplified Chinese to ChatGPT, Claude, DeepSeek, Qwen, and Kimi. Responses were evaluated by pediatric thoracic surgeons from three institutions for accuracy, completeness, and relevance, using a 6-point Likert scale. Readability was assessed using AlphaReadabilityChinese (ARC) 2.0 and the Chinese Readability Index Explorer (CRIE) 3.0. Understandability, actionability, and overall quality were evaluated with the Chinese Patient Education Materials Assessment Tool for Printable Materials (C-PEMAT-P) and the Global Quality Score (GQS). Friedman tests compared the models, followed by Holm-adjusted Wilcoxon signed-rank tests. Results All models achieved mean accuracy, completeness, and relevance scores above 4.9 on the 6-point scale, but the leading model differed by dimension. Claude had the highest mean accuracy (5.39 ± 0.28), completeness (5.22 ± 0.22), and GQS (4.80 ± 0.41), while DeepSeek had the highest relevance (5.42 ± 0.27). Qwen was the least readable: its median CRIE grade was 7.0, compared with 5.5 to 6.0 for the other models. Only 23.3% of its responses were at Grades 1–6, compared with 66.7–86.7% for the others. Overall C-PEMAT-P scores also differed ( p = 0.003), with Kimi showing the highest numerical mean total (12.17 ± 0.75). Qwen combined the highest actionability (2.57 ± 0.50) with the lowest understandability (9.47 ± 0.57) and GQS (3.10 ± 0.71). Conclusion Leading LLMs generally provided accurate, complete, and relevant Simplified Chinese answers to common pediatric PE questions, but no model performed best on every dimensions. LLM outputs should therefore be regarded as a supervised educational aid that require expert verification and adaptation to the health literacy of the intended audience, rather than as substitutes for specialist counseling.

Frontiers in Public HealthVol. 14
National Taiwan University of Science and Technology (TW), Shanghai Jiao Tong University (CN), Nantong University (CN), Shanghai Dianji University (CN), Shanghai Children's Hospital (CN), National Kaohsiung University of Science and Technology (TW)
Good health and well-being
Openalex Percentile: Top 19%
Artificial Intelligence in Healthcare and Education
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