Efficacy of Nasal Intermittent Positive Pressure Ventilation (NIPPV) in Newborn Patients With Respiratory Distress

Objective: To determine the effectiveness of Nasal Intermittent Positive Pressure Ventilation (NIPPV) in neonates presenting with respiratory distress in terms of need and duration of mechanical ventilation. Study Design: Prospective analytical study Place and Duration of Study: Department of Pediatrics, Pak Emirates Military Hospital (PEMH), Rawalpindi, Pakistan, from Mar 24 to Mar 25. Methodology: This study included 102 newborn patients who were presented with respiratory distress. All newborn patients who had respiratory distress were placed on NIPPV. Efficacy of NIPPV was determined by factors such as the final outcome of neonates, total duration of stay in the neonatal intensive care unit, need for mechanical ventilation, and development of any complications. Results: The results of the study showed that out of a total of 102 neonates included in the study, 55(53.9%) were male and 47(46.1%) were female babies. 65(63.7%) Babies were born via LSCS while 37(36.3%) were born via SVD. Neonates born via LSCS required a longer duration on NIPV, mechanical ventilation, and had a statistically significantly longer duration of stay in NICU. Initial blood lactate >5 mmol/L was significantly associated with longer NIPPV duration, increased need for mechanical ventilation, and increased mortality rates. Conclusion: Birth weight of babies and lactate level at birth were significantly associated with morbidity and mortality in neonates treated with NIPPV.