A REVIEW ON IMPACT OF POST COATING THERMAL TREATMENT ON THE QUALITY AND DRUG RELEASE OF FILM COATED TABLET (TRAMADOL)

Tablets are among the most convenient and preferred oral dosage forms because of their many advantages, including ease of administration, high patient compliance, and cost-effectiveness. Among the multiple steps in pharmaceutical manufacturing of tablets, coating is a critical process that is often used for functional and aesthetic reasons. Among three types of tablet-coating processes (sugar coating, film coating, and press coating), film coating is the most widely used approach to solve various issues encountered during manufacturing, transport, storage, and clinical use of drug products. For example, tablets containing active pharmaceutical ingredients (APIs) sensitive to light, oxidation, or moisture can be protected by film coating, leading to increased stability of drug products during manufacturing and storage.[1,2]