The Effect of Roselle Tea (Hibiscus Sabdariffa L.) on Prostaglandin F₂α Levels and Pain Intensity in Reproductive-Aged Women with Primary Dysmenorrhea

Primary dysmenorrhea is a common reproductive health problem among women of reproductive age and is closely associated with increased prostaglandin F₂α production, which induces uterine contractions, vasoconstriction, ischemia, and menstrual pain. Roselle (Hibiscus sabdariffa L.) contains bioactive compounds with potential anti-inflammatory and antioxidant activities. Objective: This study aimed to evaluate the effect of roselle tea on prostaglandin F₂α levels and pain intensity in women of reproductive age with primary dysmenorrhea. Methods: A quasi-experimental two-group pretest-posttest design was conducted among 40 women with primary dysmenorrhea who were selected using purposive sampling and divided into intervention and control groups (n=20 each). The intervention group received 2 g of roselle tea brewed in 200 mL of warm water twice daily for three consecutive days, while the control group received 200 mL of warm water twice daily. Prostaglandin F₂α levels and pain intensity were measured at pretest, day 2, and day 3. Results: In the intervention group, mean prostaglandin F₂α levels decrease from 317.63±36.30 at pretest to 247.72±36.16 on day 2 and 183.62±47.33 on day 3 (p<0.001). Mean pain intensity also decreases from 2.35±0.489 to 2.00±0.324 and 1.10±0.718, respectively (p<0.001). The reductions are descriptively greater than those observed in the control group. Conclusion: Roselle tea shows potential as a complementary intervention for reducing prostaglandin F₂α levels and pain intensity in women with primary dysmenorrhea

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Journal
JURNAL FARMASIMED (JFM)
Published
2026-10-30
DOI
https://doi.org/10.35451/jfm.v9i1.4069
Primary Topic
Hibiscus Plant Research Studies
Type
article
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article

The Effect of Roselle Tea (Hibiscus Sabdariffa L.) on Prostaglandin F₂α Levels and Pain Intensity in Reproductive-Aged Women with Primary Dysmenorrhea

Asti Pratiwi, Mayang Citra Hariati, Dwi Esti Handayani
JURNAL FARMASIMED (JFM)
Hibiscus Plant Research Studies
article

The Effect of Roselle Tea (Hibiscus Sabdariffa L.) on Prostaglandin F₂α Levels and Pain Intensity in Reproductive-Aged Women with Primary Dysmenorrhea

Asti Pratiwi, Mayang Citra Hariati, Dwi Esti Handayani
article en

Abstract

Primary dysmenorrhea is a common reproductive health problem among women of reproductive age and is closely associated with increased prostaglandin F₂α production, which induces uterine contractions, vasoconstriction, ischemia, and menstrual pain. Roselle (Hibiscus sabdariffa L.) contains bioactive compounds with potential anti-inflammatory and antioxidant activities. Objective: This study aimed to evaluate the effect of roselle tea on prostaglandin F₂α levels and pain intensity in women of reproductive age with primary dysmenorrhea. Methods: A quasi-experimental two-group pretest-posttest design was conducted among 40 women with primary dysmenorrhea who were selected using purposive sampling and divided into intervention and control groups (n=20 each). The intervention group received 2 g of roselle tea brewed in 200 mL of warm water twice daily for three consecutive days, while the control group received 200 mL of warm water twice daily. Prostaglandin F₂α levels and pain intensity were measured at pretest, day 2, and day 3. Results: In the intervention group, mean prostaglandin F₂α levels decrease from 317.63±36.30 at pretest to 247.72±36.16 on day 2 and 183.62±47.33 on day 3 (p<0.001). Mean pain intensity also decreases from 2.35±0.489 to 2.00±0.324 and 1.10±0.718, respectively (p<0.001). The reductions are descriptively greater than those observed in the control group. Conclusion: Roselle tea shows potential as a complementary intervention for reducing prostaglandin F₂α levels and pain intensity in women with primary dysmenorrhea

JURNAL FARMASIMED (JFM)Vol. 9(1)
Institut Kesehatan Medistra Lubuk Pakam (ID)
Good health and well-being
Openalex Percentile: Top 10%
Hibiscus Plant Research Studies
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