When the skin speaks but the heart remains silent: acute rheumatic fever with three major Jones manifestations without carditis

Acute rheumatic fever is classically associated with carditis, particularly when erythema marginatum and subcutaneous nodules are present. We report a 13-year-old boy who fulfilled three major Jones manifestations-migratory polyarthritis, erythema marginatum, and subcutaneous nodules-supported by evidence of recent streptococcal infection, yet had no clinical, electrocardiographic, or echocardiographic evidence of carditis on serial assessment over three months. Serial photographs documented the evolving morphology of erythema marginatum in dark skin. A transient ocular inflammatory episode occurred during convalescence. This case highlights an uncommon phenotype of acute rheumatic fever and underscores the importance of recognising major extracardiac manifestations even when the heart remains unaffected.

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Publication Details

Journal
Cardiology in the Young
Published
2026-10-30
DOI
https://doi.org/10.1017/s1047951126124743
Primary Topic
Streptococcal Infections and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

When the skin speaks but the heart remains silent: acute rheumatic fever with three major Jones manifestations without carditis

Prateep Paul, Anil Kumar Singhi
1 links
Cardiology in the Young
Streptococcal Infections and Treatments
article

When the skin speaks but the heart remains silent: acute rheumatic fever with three major Jones manifestations without carditis

Prateep Paul, Anil Kumar Singhi
article en

Abstract

Acute rheumatic fever is classically associated with carditis, particularly when erythema marginatum and subcutaneous nodules are present. We report a 13-year-old boy who fulfilled three major Jones manifestations-migratory polyarthritis, erythema marginatum, and subcutaneous nodules-supported by evidence of recent streptococcal infection, yet had no clinical, electrocardiographic, or echocardiographic evidence of carditis on serial assessment over three months. Serial photographs documented the evolving morphology of erythema marginatum in dark skin. A transient ocular inflammatory episode occurred during convalescence. This case highlights an uncommon phenotype of acute rheumatic fever and underscores the importance of recognising major extracardiac manifestations even when the heart remains unaffected.

Cardiology in the Young
Charnock Hospital (IN), Manipal Hospital (IN)
Good health and well-being
Openalex Percentile: Top 10%
Streptococcal Infections and Treatments
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