Analysis Quantitativ Qualitativ use Antibiotic in Surgical Inpatient at Dr. Soebandi Hospital Jember

Background: Prophylactic antibiotics are generally administered to patients undergoing surgical procedures to reduce the risk of surgical site infections. Aim: This study employed a cross-sectional design with retrospective data collection from the medical records of surgical inpatients at Dr. Soebandi Regional Hospital, Jember, during the period of January–June 2025. A total of 336 patients were selected using purposive sampling. Data were obtained from medical records, electronic medical records, and the hospital information system. Quantitative analysis was performed using the ATC/DDD and DU 90% methods, while qualitative analysis was conducted using the Gyssens method. Result: The results showed that the majority of surgical patients at RSD Dr. Soebandi Jember were female (64.29%) compared to male (35.71%), with a predominant length of stay of 4 days. Prophylactic antibiotic therapy was administered to 96.43% of surgical patients, while 3.57% did not receive prophylaxis. The most frequently used antibiotics were Cefazoline, with a DDD of 13.24/100 bed-days, and Ceftriaxone, with 9.52/100 bed-days, both of which were included in the DU 90% segment. The number of patients receiving rational antibiotic therapy was 182 cases (54.17%). Conclusion However, several issues were identified: ineffective antibiotic use for surgical procedures was found in 134 cases (39.88%), availability of more cost-effective alternatives in 50 cases (14.88%), and prolonged antibiotic use post-surgery in 16 cases (4.76%).