Utility of Intracerebral Hemorrhage Score in Predicting 30-Day Functional Outcome in Patients with Spontaneous Intracerebral Hemorrhage

ABSTRACT Background: Functional outcome after spontaneous intracerebral hemorrhage (ICH) can be estimated early and can aid clinical assessment and care planning. This study was designed to assess the admission ICH Score for predicting functional outcome at 30 days. Methods: This was a prospective observational study of 135 adults with spontaneous ICH confirmed on CT scan who presented to an emergency department in Pune, India. The admission ICH Score was assessed against the 30-day modified Rankin Scale (mRS), categorized as favorable (0–2) or poor (3–6). Association and discrimination were assessed by regression and receiver operating characteristic analyses. Results: At 30 days, 71 (52.6%) patients had favorable outcomes and 64 (47.4%) patients had poor outcomes. The ICH Score was highly correlated with mRS (Spearman ρ = 0.848, p < 0.001). Each one-point increase was associated with increased odds of poor outcome (OR 6.59, 95% CI 3.60–12.08). The AUC was 0.910 (95% CI 0.859–0.955). The cutoff value of ≥2 had 87.5% sensitivity and 87.3% specificity. Conclusions: In this cohort, the ICH Score at admission had good discrimination for poor functional outcome at 30 days. Keywords: Intracerebral hemorrhage; ICH Score; modified Rankin Scale; functional outcome; prognosis.