The method of counter differentiation in analysis of co-morbid relationships of arterial hypertension

The article presents the results of large-scale retrospective epidemiological study (n=259,388 patients) carried out in the N. A. Semashko National Research Institute of Public Health. The purpose of the study is to assess direction and strength of comorbid relationships of arterial hypertension (AH) using the original method of counter differentiation. This method permits to separately analyze afferent (influence of other diseases on risk of developing AH) and efferent (influence of AH on risk of development of other diseases) associations in various age groups ranging from 10 to 90 years and older.It is established that AH almost never occurs in isolation since statistically highly significant associations (p