ICH M12 Draft OATP1B1 R-value ≥ 1.25: Verify Before Committing

ICH M12 Draft OATP1B1 R-value ≥ 1.25 maps to 19% of statin NDAs; learn exactly what to verify before committing to a new clinical drug-drug interaction study. Independent technical note mirroring the canonical version: https://aidrugsearch.com/blog/ich-m12-draft-oatp1b1-r-value-125-verify-before-committing.php Sources consulted: https://www.bluusun.com/

Authors

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-10-29
DOI
https://doi.org/10.5281/zenodo.23784119
Primary Topic
Pharmacogenetics and Drug Metabolism
Type
preprint
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preprint

ICH M12 Draft OATP1B1 R-value ≥ 1.25: Verify Before Committing

Madison Hayes
1 links
Zenodo (CERN European Organization for Nuclear Research)
Pharmacogenetics and Drug Metabolism
preprint

ICH M12 Draft OATP1B1 R-value ≥ 1.25: Verify Before Committing

Madison Hayes
preprint en

Abstract

ICH M12 Draft OATP1B1 R-value ≥ 1.25 maps to 19% of statin NDAs; learn exactly what to verify before committing to a new clinical drug-drug interaction study. Independent technical note mirroring the canonical version: https://aidrugsearch.com/blog/ich-m12-draft-oatp1b1-r-value-125-verify-before-committing.php Sources consulted: https://www.bluusun.com/

Zenodo (CERN European Organization for Nuclear Research)
Good health and well-being
Pharmacogenetics and Drug Metabolism
DOIOpen Access PDFOpenAlex
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ICH M12 Draft OATP1B1 R-value ≥ 1.25: Verify Before Committing — Madison Hayes · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS