Prognostic value of histomorphological and immunohistochemical parameters in gastrointestinal stromal tumors.
<0.001). No statistically significant associations were observed between prognostic risk groups and CD34, smooth muscle actin, desmin, or S-100 expression. These findings indicate that histomorphological features, such as necrosis, growth pattern, and cellular atypia, together with the Ki-67 proliferation index, may serve as valuable adjunctive prognostic markers in GISTs, complementing conventional risk stratification systems.
Authors
- Hasan İlyas Özardalı (ORCID: https://orcid.org/0000-0002-1239-599X)
- Hasan Nadir Rana (ORCID: https://orcid.org/0000-0003-3577-1297)
- Murat Akıcı (ORCID: https://orcid.org/0000-0001-6739-0670)
- Betül Demirciler Yavaş (ORCID: https://orcid.org/0000-0002-1305-7597)
- Murat Araz (ORCID: https://orcid.org/0000-0002-4632-9501)
- Mükremın Uysal (ORCID: https://orcid.org/0000-0002-8524-0665)
- Mehmet Özer
Institutions
- Necmettin Erbakan University (TR)
- Sağlık Bilimleri Üniversitesi (TR)
- Antalya IVF (TR)
- S.B.Ü. Bursa Yüksek İhtisas Eğitim ve Araştırma Hastanesi (TR)
- Afyonkarahisar Sağlık Bilimleri Üniversitesi (TR)
Publication Details
- Journal
- PubMed
- Published
- 2026-10-29
- DOI
- https://doi.org/10.14670/hh-25-164
- Primary Topic
- Gastrointestinal Tumor Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00