Don't discard the supernatant: pleural fluid cfDNA for molecular profiling in lung cancer

Pleural fluid supernatant cfDNA should be routinely preserved and can already be used selectively for molecular profiling in NSCLC, while broader implementation requires prospective clinical validation.

Authors

Publication Details

Journal
European Respiratory Journal
Published
2026-10-29
DOI
https://doi.org/10.1183/13993003.01861-2026
Primary Topic
Cancer Genomics and Diagnostics
Type
article
Field-Weighted Citation Impact
0.00
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article

Don't discard the supernatant: pleural fluid cfDNA for molecular profiling in lung cancer

José Manuel Porcel
European Respiratory Journal
Cancer Genomics and Diagnostics
article

Don't discard the supernatant: pleural fluid cfDNA for molecular profiling in lung cancer

José Manuel Porcel
article en

Abstract

Pleural fluid supernatant cfDNA should be routinely preserved and can already be used selectively for molecular profiling in NSCLC, while broader implementation requires prospective clinical validation.

European Respiratory Journal
Openalex Percentile: Top 16%
Cancer Genomics and Diagnostics
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Don't discard the supernatant: pleural fluid cfDNA for molecular profiling in lung cancer — José Manuel Porcel · European Respiratory Journal (2026) | TGRS Research Map | TGRS