1-(1-Methyl-5-thiocyanato-1H-pyrrol-2-yl)-3-nitro-1H-1,2,4-triazole
A two-stage synthesis of the novel compound 1-(1-methyl-5-thiocyanato-1H-pyrrol-2-yl)-3-nitro-1H-1,2,4-triazole utilizing electrochemistry as an environmentally benign tool is reported. The structure of the target molecule was confirmed by 1H and 13C NMR spectroscopy and HRMS. The compound exhibits antibacterial and antifungal activity comparable to chloramphenicol, ciprofloxacin, and fluconazole.
Authors
- Vladimir A. Kokorekin (ORCID: https://orcid.org/0000-0002-7124-8738)
- Vladimir M. Khodonov
- Stanislava R. Usova
- Natalia V. Gorphinchenko
- Anna M. Sukhanova
Institutions
- Russian Academy of Sciences (RU)
- Sechenov University (RU)
- N.D. Zelinsky Institute of Organic Chemistry (RU)
Publication Details
- Journal
- Molbank
- Published
- 2026-10-29
- DOI
- https://doi.org/10.3390/m2249
- Primary Topic
- Structural and Chemical Analysis of Organic and Inorganic Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Russian Science Foundation