Mitochondrial genome editing reveals the impact of complex I heteroplasmic variants on human neurogenesis

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Publication Details

Journal
bioRxiv (Cold Spring Harbor Laboratory)
Published
2026-10-29
DOI
https://doi.org/10.64898/2026.10.28.762518
Primary Topic
Mitochondrial Function and Pathology
Type
preprint

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preprint

Mitochondrial genome editing reveals the impact of complex I heteroplasmic variants on human neurogenesis

Alessandro Prigione, Isabella Tolle, Claudio Fiorini, Emanuela Bottani et al.
2 links
bioRxiv (Cold Spring Harbor Laboratory)
Mitochondrial Function and Pathology
preprint

Mitochondrial genome editing reveals the impact of complex I heteroplasmic variants on human neurogenesis

Alessandro Prigione, Isabella Tolle, Claudio Fiorini, Emanuela Bottani, Diran Agaid Herebian, Annika Zink, Paweł Lisowski, Ertan Mayatepek, Valeria Balmaceda, Valério Carelli, Jochen Dobner, Andrea Rossi, Alberto Pietro Pasti, Florian Tschuschke
preprint en

Abstract

No abstract available for this paper.
bioRxiv (Cold Spring Harbor Laboratory)
University of Verona (IT), Max Delbrück Center (DE), Düsseldorf University Hospital (DE), Leibniz Institute of Environmental Medicine (DE), Heinrich Heine University Düsseldorf (DE), University of Bologna (IT)
European Commission, Deutsche Forschungsgemeinschaft, HORIZON EUROPE Framework Programme, Leibniz-Gemeinschaft
Good health and well-being
Mitochondrial Function and Pathology
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Mitochondrial genome editing reveals the impact of complex I heteroplasmic variants on human neurogenesis — Alessandro Prigione, Isabella Tolle, et al. · bioRxiv (Cold Spring Harbor Laboratory) (2026) | TGRS Research Map | TGRS