Human infection with an ape Plasmodium vivax-like parasite

An unusually divergent Plasmodium vivax parasite was reported in a Swedish patient with recent travel. Using whole-genome sequencing, we show that the infection was caused by a strain of ape P. vivax-like, providing evidence of the zoonotic potential of these parasites that infect wild gorillas and chimpanzees in central Africa.

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Publication Details

Journal
bioRxiv (Cold Spring Harbor Laboratory)
Published
2026-10-29
DOI
https://doi.org/10.64898/2026.10.23.757543
Primary Topic
Malaria Research and Control
Type
preprint

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preprint

Human infection with an ape Plasmodium vivax-like parasite

Christen Rune Stensvold, Paul M. Sharp, Henrik Vedel Nielsen, Thomas Booth et al.
1 links
bioRxiv (Cold Spring Harbor Laboratory)
Malaria Research and Control
preprint

Human infection with an ape Plasmodium vivax-like parasite

Christen Rune Stensvold, Paul M. Sharp, Henrik Vedel Nielsen, Thomas Booth, Tue Sparholt Jørgensen, John Kerr White, Jonathan Szeps
preprint en

Abstract

An unusually divergent Plasmodium vivax parasite was reported in a Swedish patient with recent travel. Using whole-genome sequencing, we show that the infection was caused by a strain of ape P. vivax-like, providing evidence of the zoonotic potential of these parasites that infect wild gorillas and chimpanzees in central Africa.

bioRxiv (Cold Spring Harbor Laboratory)
Statens Serum Institut (DK), Karolinska University Hospital (SE), Karolinska Institutet (SE), Technical University of Denmark (DK), University of Edinburgh (GB)
Novo Nordisk
Good health and well-being
Malaria Research and Control
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