Lung Abscess and Empyema Caused by Panton‐Valentine Leukocidin‐Positive Methicillin‐Resistant Staphylococcus aureus ψUSA300 Strain in a Previously Healthy Adult

ABSTRACT PVL‐positive ψUSA300 CA‐MRSA is increasingly identified in Japan and is primarily associated with skin and soft tissue infections; respiratory infections caused by this clone remain rare. We report a 49‐year‐old healthy woman with lung abscess and empyema caused by PVL‐positive ψUSA300, successfully treated with vancomycin and linezolid. This case expands the known clinical spectrum of ψUSA300 and underscores the need for CA‐MRSA consideration in otherwise healthy patients with severe pulmonary infections.

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Publication Details

Journal
Respirology Case Reports
Published
2026-10-28
DOI
https://doi.org/10.1002/rcr2.70772
Primary Topic
Antimicrobial Resistance in Staphylococcus
Type
article
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article

Lung Abscess and Empyema Caused by Panton‐Valentine Leukocidin‐Positive Methicillin‐Resistant Staphylococcus aureus ψUSA300 Strain in a Previously Healthy Adult

柳澤 麻子, Hidehito Matsui, Hiroshi Kojima, Hidefumi Shimizu et al.
Respirology Case Reports
Antimicrobial Resistance in Staphylococcus
article

Lung Abscess and Empyema Caused by Panton‐Valentine Leukocidin‐Positive Methicillin‐Resistant Staphylococcus aureus ψUSA300 Strain in a Previously Healthy Adult

柳澤 麻子, Hidehito Matsui, Hiroshi Kojima, Hidefumi Shimizu, Daisuke Kishikawa, Yuri Emori, Hodaka Serizawa, Rikako Nakamura
article en

Abstract

ABSTRACT PVL‐positive ψUSA300 CA‐MRSA is increasingly identified in Japan and is primarily associated with skin and soft tissue infections; respiratory infections caused by this clone remain rare. We report a 49‐year‐old healthy woman with lung abscess and empyema caused by PVL‐positive ψUSA300, successfully treated with vancomycin and linezolid. This case expands the known clinical spectrum of ψUSA300 and underscores the need for CA‐MRSA consideration in otherwise healthy patients with severe pulmonary infections.

Respirology Case ReportsVol. 14(11)
Japan Community Healthcare Organization (JP), Tokyo Shinjuku Medical Center (JP), Ōmura Satoshi Memorial Institute (JP), Kitasato University (JP)
Openalex Percentile: Top 12%
Antimicrobial Resistance in Staphylococcus
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