Pinhole‐Like Central Bronchial Narrowing: A Rare Reversible Manifestation of Eosinophilic Bronchial Inflammation

Recurrent atelectasis is occasionally encountered in clinical practice but may be attributed to repeated respiratory infections without thorough investigation, potentially delaying the diagnosis of the underlying cause. We report a 78-year-old woman with well-controlled asthma who developed recurrent right middle lobe and lingular atelectasis. Bronchoscopy revealed severe pinhole-like narrowing of multiple central bronchi. Although allergic bronchopulmonary mycosis and post-infectious cicatricial stenosis were initially considered, characteristic eosinophilic mucus impaction was absent, and endobronchial biopsy demonstrated marked eosinophilic inflammation of the bronchial wall with airway remodelling. Oral corticosteroid therapy resulted in resolution of the atelectasis and improvement of the bronchial narrowing. This case highlights eosinophilic bronchial inflammation as a rare but reversible cause of central bronchial narrowing and underscores the diagnostic value of endobronchial biopsy in patients with unexplained recurrent atelectasis.

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Publication Details

Journal
Respirology Case Reports
Published
2026-10-29
DOI
https://doi.org/10.1002/rcr2.70802
Primary Topic
Asthma and respiratory diseases
Type
article
Field-Weighted Citation Impact
0.00

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article

Pinhole‐Like Central Bronchial Narrowing: A Rare Reversible Manifestation of Eosinophilic Bronchial Inflammation

Jun Araya, Takanori Numata, Takaaki Kitayama, Makiko Takatsuka et al.
1 links
Respirology Case Reports
Asthma and respiratory diseases
article

Pinhole‐Like Central Bronchial Narrowing: A Rare Reversible Manifestation of Eosinophilic Bronchial Inflammation

Jun Araya, Takanori Numata, Takaaki Kitayama, Makiko Takatsuka, Ryusuke Kizawa, Masahiro Yoshida, Zenya Saito, Kohei Minekawa
article en

Abstract

Recurrent atelectasis is occasionally encountered in clinical practice but may be attributed to repeated respiratory infections without thorough investigation, potentially delaying the diagnosis of the underlying cause. We report a 78-year-old woman with well-controlled asthma who developed recurrent right middle lobe and lingular atelectasis. Bronchoscopy revealed severe pinhole-like narrowing of multiple central bronchi. Although allergic bronchopulmonary mycosis and post-infectious cicatricial stenosis were initially considered, characteristic eosinophilic mucus impaction was absent, and endobronchial biopsy demonstrated marked eosinophilic inflammation of the bronchial wall with airway remodelling. Oral corticosteroid therapy resulted in resolution of the atelectasis and improvement of the bronchial narrowing. This case highlights eosinophilic bronchial inflammation as a rare but reversible cause of central bronchial narrowing and underscores the diagnostic value of endobronchial biopsy in patients with unexplained recurrent atelectasis.

Respirology Case ReportsVol. 14(11)
Jikei University School of Medicine (JP), Atsugi City Hospital (JP)
Google
Good health and well-being
Openalex Percentile: Top 13%
Asthma and respiratory diseases
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Pinhole‐Like Central Bronchial Narrowing: A Rare Reversible Manifestation of Eosinophilic Bronchial Inflammation — Jun Araya, Takanori Numata, et al. · Respirology Case Reports (2026) | TGRS Research Map | TGRS