Multiple cartilaginous exostosis in a feline: Case report

Multiple cartilaginous exostoses (MCE), or osteochondromatosis, is a benign neoplasm characterized by the presence of nodules on the bone surface. In felines, the condition may be associated with feline leukemia virus (FeLV) infection and genetic mutations. This study reports the case of a 2-year-old cat diagnosed with MCE. The animal presented with cachexia, hyporexia, dehydration, and increased bone volume in multiple anatomical regions. Radiographic examination revealed proliferative sclerotic lesions, and histopathology confirmed osteochondrogenic proliferation consistent with MCE. Initial treatment included doxycycline and prednisolone. After 30 days, the cat showed clinical improvement; however, the osseous proliferations continued to increase in size. Subsequent radiographic evaluation demonstrated marked lesion progression, accompanied by worsening clinical signs. Due to the extent of the lesions and the unfavorable clinical condition, euthanasia was elected. This report highlights the clinical and imaging features of MCE in a young FeLV-positive cat and emphasizes the importance of early diagnosis and imaging follow-up in the management of affected patients.