Code and data for: Genomic deletion and duplication effects on cognitive ability are asymmetrically distributed along the cortical sensorimotor–association hierarchy

This record contains the code, gene sets, and derived summary statistics needed to reproduce the figures and statistical analyses in Kumar, Kazem et al., “Genomic deletion and duplication effects on cognitive ability are asymmetrically distributed along the cortical sensorimotor–association hierarchy”It includes the cerebral-cortex gene-set burden analysis (CC-GSBA) pipeline with synthetic toy data, R Markdown code for all main and supplementary figures, the 180 Glasser cortical gene sets, and summary-level run outputs. No individual-level participant data are included.Licences: code under MIT; data, gene sets, figures and documentation under CC BY 4.0.Previous version:v1: “Mirror effect of genomic deletions and duplications on cognitive ability across the human cerebral cortex” https://doi.org/10.1101/2025.01.06.631492.

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Zenodo (CERN European Organization for Nuclear Research)
Published
2026-10-29
DOI
https://doi.org/10.5281/zenodo.17593038
Primary Topic
Genomic variations and chromosomal abnormalities
Type
article
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article

Code and data for: Genomic deletion and duplication effects on cognitive ability are asymmetrically distributed along the cortical sensorimotor–association hierarchy

Sayeh Kazem, Kuldeep Kumar
1 links
Zenodo (CERN European Organization for Nuclear Research)
Genomic variations and chromosomal abnormalities
article

Code and data for: Genomic deletion and duplication effects on cognitive ability are asymmetrically distributed along the cortical sensorimotor–association hierarchy

Sayeh Kazem, Kuldeep Kumar
article en

Abstract

This record contains the code, gene sets, and derived summary statistics needed to reproduce the figures and statistical analyses in Kumar, Kazem et al., “Genomic deletion and duplication effects on cognitive ability are asymmetrically distributed along the cortical sensorimotor–association hierarchy”It includes the cerebral-cortex gene-set burden analysis (CC-GSBA) pipeline with synthetic toy data, R Markdown code for all main and supplementary figures, the 180 Glasser cortical gene sets, and summary-level run outputs. No individual-level participant data are included.Licences: code under MIT; data, gene sets, figures and documentation under CC BY 4.0.Previous version:v1: “Mirror effect of genomic deletions and duplications on cognitive ability across the human cerebral cortex” https://doi.org/10.1101/2025.01.06.631492.

Zenodo (CERN European Organization for Nuclear Research)
Centre Hospitalier Universitaire Sainte-Justine (CA), Université de Montréal (CA)
Openalex Percentile: Top 15%
Genomic variations and chromosomal abnormalities
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