3-Methyl-1-phenyl-4-thioaroylpyrazolones—Synthesis, Preferred Solid-State Geometry and an Atypical Side Product of Lawesson’s Thionation
A series of five novel 3-methyl-1-phenyl-4-(4-thioaroyl)-pyrazol-5-ones is obtained in excellent yields by thionation of the corresponding O-analogues with Lawesson’s reagent. The products are characterized in solution and solid phase. It is found that only mono-thionation occurs and that the products exist in enol-thione forms. Atypical side products are isolated and characterized. The preferred solid state forms are analyzed and compared with those of the corresponding O-analogues.
Authors
- Vanya B. Kurteva (ORCID: https://orcid.org/0000-0001-8703-0066)
- Rusi Rusew (ORCID: https://orcid.org/0000-0003-1274-0885)
- Boris Lubomirov Shivachev (ORCID: https://orcid.org/0000-0001-8765-6536)
- Zhanina S. Petkova (ORCID: https://orcid.org/0009-0003-4101-7036)
- Magdalena Angelova
Institutions
- Bulgarian Academy of Sciences (BG)
- Medical University Plovdiv (BG)
- Institute of Mineralogy and Crystallography "Acad. Ivan Kostov" Bulgarian Academy of Sciences (BG)
Publication Details
- Journal
- Organics
- Published
- 2026-10-29
- DOI
- https://doi.org/10.3390/org7040046
- Primary Topic
- Synthesis and Reactivity of Sulfur-Containing Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Bulgarian National Science Fund