Genome sequence of Clostridioides difficile PRB1128, a RT023 strain containing a mobile genetic element allowing for xylitol utilization

ABSTRACT Clade 3 strains of Clostridioides difficile , dominated by PCR ribotype 023 (RT023) strains, remain the least well studied in the phylogeny. We sequenced a strain of RT023 C. difficile (PRB1128) to gain molecular genetic insights and add to the limited repository of RT023 genomes in existence.

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Publication Details

Journal
Microbiology Resource Announcements
Published
2026-10-29
DOI
https://doi.org/10.1128/mra.00907-26
Primary Topic
Clostridium difficile and Clostridium perfringens research
Type
article
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article

Genome sequence of Clostridioides difficile PRB1128, a RT023 strain containing a mobile genetic element allowing for xylitol utilization

Robert A. Britton, Wiep Klaas Smits, Katherine J. Wozniak, Jeroen Corver et al.
3 links
Microbiology Resource Announcements
Clostridium difficile and Clostridium perfringens research
article

Genome sequence of Clostridioides difficile PRB1128, a RT023 strain containing a mobile genetic element allowing for xylitol utilization

Robert A. Britton, Wiep Klaas Smits, Katherine J. Wozniak, Jeroen Corver, Ed J. Kuijper
article en

Abstract

ABSTRACT Clade 3 strains of Clostridioides difficile , dominated by PCR ribotype 023 (RT023) strains, remain the least well studied in the phylogeny. We sequenced a strain of RT023 C. difficile (PRB1128) to gain molecular genetic insights and add to the limited repository of RT023 genomes in existence.

Microbiology Resource Announcements
Leiden University (NL), Baylor College of Medicine (US), Leiden University Medical Center (NL)
Openalex Percentile: Top 12%
Clostridium difficile and Clostridium perfringens research
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Genome sequence of Clostridioides difficile PRB1128, a RT023 strain containing a mobile genetic element allowing for xylitol utilization — Robert A. Britton, Wiep Klaas Smits, et al. · Microbiology Resource Announcements (2026) | TGRS Research Map | TGRS