Patient‐reported stigma toward medications for opioid use disorder: A pilot study in adults receiving inpatient treatment

BACKGROUND AND OBJECTIVES: Although medications are effective treatments for opioid use disorder (OUD), they are highly stigmatized. Our objectives were to (1) compare patient-reported stigma across medication types and (2) determine whether intention to take each medication was associated with stigma and perceived effectiveness. METHODS: Adults with OUD (N = 58) were enrolled from inpatient treatment. RESULTS: Stigma toward naltrexone was significantly lower than buprenorphine and methadone. Perceived effectiveness was strongly associated with intention to take each medication, whereas stigma was only associated with intention to take methadone. CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE: Patients reported higher stigma for agonist medications, however perceived effectiveness was more strongly associated with intention to take medication. Both knowledge about MOUD effectiveness and stigma may be valuable targets for improving MOUD uptake.

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Publication Details

Journal
American Journal on Addictions
Published
2026-10-29
DOI
https://doi.org/10.1111/ajad.70219
Primary Topic
Opioid Use Disorder Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

Patient‐reported stigma toward medications for opioid use disorder: A pilot study in adults receiving inpatient treatment

Gabriel Comas, Roger D. Weiss, Blake T. Hilton, R. Kathryn McHugh et al.
3 links
American Journal on Addictions
Opioid Use Disorder Treatment
article

Patient‐reported stigma toward medications for opioid use disorder: A pilot study in adults receiving inpatient treatment

Gabriel Comas, Roger D. Weiss, Blake T. Hilton, R. Kathryn McHugh, Reuben Hendler, Victoria R. Votaw
article en

Abstract

BACKGROUND AND OBJECTIVES: Although medications are effective treatments for opioid use disorder (OUD), they are highly stigmatized. Our objectives were to (1) compare patient-reported stigma across medication types and (2) determine whether intention to take each medication was associated with stigma and perceived effectiveness. METHODS: Adults with OUD (N = 58) were enrolled from inpatient treatment. RESULTS: Stigma toward naltrexone was significantly lower than buprenorphine and methadone. Perceived effectiveness was strongly associated with intention to take each medication, whereas stigma was only associated with intention to take methadone. CONCLUSIONS AND SCIENTIFIC SIGNIFICANCE: Patients reported higher stigma for agonist medications, however perceived effectiveness was more strongly associated with intention to take medication. Both knowledge about MOUD effectiveness and stigma may be valuable targets for improving MOUD uptake.

American Journal on Addictions
Harvard University (US), McLean Hospital (US)
Charles Engelhard Foundation
Good health and well-being
Openalex Percentile: Top 10%
Opioid Use Disorder Treatment
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