Clinical and Diagnostic Spectrum of Girls Evaluated for Suspected Precocious Puberty: A Single-Center Study

Objective: To evaluate the clinical, anthropometric, biochemical, and imaging characteristics of girls presenting with suspected precocious puberty and identify the key parameters that distinguish central precocious puberty (CPP) from benign pubertal variants.Methods: Between 2024 and 2025, 231 girls were retrospectively assessed at a single center and categorized into six diagnostic groups: central precocious puberty (CPP), rapidly progressing early puberty (R-EP), slowly progressing early puberty, premature thelarche, premature adrenarche, and normal. Clinical, anthropometric, laboratory, imaging, and treatment data were compared between the groups.Results: Age at presentation was significantly lower in the CPP and premature thelarche groups (p

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Publication Details

Journal
New Trends in Medicine Sciences
Published
2026-10-29
DOI
https://doi.org/10.56766/ntms.1955497
Primary Topic
Hypothalamic control of reproductive hormones
Type
article
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article

Clinical and Diagnostic Spectrum of Girls Evaluated for Suspected Precocious Puberty: A Single-Center Study

Semra Bahar
2 links
New Trends in Medicine Sciences
Hypothalamic control of reproductive hormones
article

Clinical and Diagnostic Spectrum of Girls Evaluated for Suspected Precocious Puberty: A Single-Center Study

Semra Bahar
article en

Abstract

Objective: To evaluate the clinical, anthropometric, biochemical, and imaging characteristics of girls presenting with suspected precocious puberty and identify the key parameters that distinguish central precocious puberty (CPP) from benign pubertal variants.Methods: Between 2024 and 2025, 231 girls were retrospectively assessed at a single center and categorized into six diagnostic groups: central precocious puberty (CPP), rapidly progressing early puberty (R-EP), slowly progressing early puberty, premature thelarche, premature adrenarche, and normal. Clinical, anthropometric, laboratory, imaging, and treatment data were compared between the groups.Results: Age at presentation was significantly lower in the CPP and premature thelarche groups (p

New Trends in Medicine SciencesVol. 7(3)
İstanbul Eğitim ve Araştırma Hastanesi (TR), Ege Üniversitesi Tıp Fakültesi Hastanesi (TR)
Good health and well-being
Openalex Percentile: Top 11%
Hypothalamic control of reproductive hormones
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