Differential diagnosis and teratment of intestinal dyspepsia, malabsorption.

Background: Abdominal discomfort, bloating, altered bowel habits, and chronic diarrhea are common presentations in hospital and outpatient practice. They may reflect functional gastrointestinal disorders, infection, inflammation, impaired digestion, or reduced nutrient absorption. Objective: To summarize the differential diagnosis, clinical assessment, investigations, and evidence-based management of intestinal symptoms associated with suspected malabsorption. Methods: This educational narrative review synthesizes clinical principles and selected guidance on celiac disease, lactose intolerance, exocrine pancreatic insufficiency, irritable bowel syndrome, inflammatory bowel disease, intestinal infection, and related disorders. It is not a new systematic review or original clinical study. Results: Symptom overlap makes diagnosis challenging. A structured history and examination, recognition of alarm features, and targeted blood, stool, serological, endoscopic, or breath tests can help identify the cause. Management is cause-specific and may include dietary intervention, medications, enzyme replacement, treatment of infection or inflammation, and correction of nutritional deficiencies.

Authors

Publication Details

Journal
Open Science Framework
Published
2026-10-28
DOI
https://doi.org/10.17605/osf.io/b29ry
Primary Topic
Celiac Disease Research and Management
Type
article
Field-Weighted Citation Impact
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article

Differential diagnosis and teratment of intestinal dyspepsia, malabsorption.

Turdaliev samatbek Orozalievich, Arokiasamy ghill, Geetha
Open Science Framework
Celiac Disease Research and Management
article

Differential diagnosis and teratment of intestinal dyspepsia, malabsorption.

Turdaliev samatbek Orozalievich, Arokiasamy ghill, Geetha
article en

Abstract

Background: Abdominal discomfort, bloating, altered bowel habits, and chronic diarrhea are common presentations in hospital and outpatient practice. They may reflect functional gastrointestinal disorders, infection, inflammation, impaired digestion, or reduced nutrient absorption. Objective: To summarize the differential diagnosis, clinical assessment, investigations, and evidence-based management of intestinal symptoms associated with suspected malabsorption. Methods: This educational narrative review synthesizes clinical principles and selected guidance on celiac disease, lactose intolerance, exocrine pancreatic insufficiency, irritable bowel syndrome, inflammatory bowel disease, intestinal infection, and related disorders. It is not a new systematic review or original clinical study. Results: Symptom overlap makes diagnosis challenging. A structured history and examination, recognition of alarm features, and targeted blood, stool, serological, endoscopic, or breath tests can help identify the cause. Management is cause-specific and may include dietary intervention, medications, enzyme replacement, treatment of infection or inflammation, and correction of nutritional deficiencies.

Open Science Framework
Good health and well-being
Openalex Percentile: Top 10%
Celiac Disease Research and Management
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