What are the common genetic mutations associated with leiomyosarcoma, and how do they influence treatment decisions?

No direct evidence specifically links genetic mutations in leiomyosarcoma with tailored treatment decisions. However, mutations in BRCA1/2, ATRX, and TP53 may guide use of targeted therapies, emphasizing the role of comprehensive molecular profiling in management.

Authors

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-10-28
DOI
https://doi.org/10.5281/zenodo.23736597
Primary Topic
Sarcoma Diagnosis and Treatment
Type
article
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article

What are the common genetic mutations associated with leiomyosarcoma, and how do they influence treatment decisions?

Tripdatabase
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Zenodo (CERN European Organization for Nuclear Research)
Sarcoma Diagnosis and Treatment
article

What are the common genetic mutations associated with leiomyosarcoma, and how do they influence treatment decisions?

Tripdatabase
article en

Abstract

No direct evidence specifically links genetic mutations in leiomyosarcoma with tailored treatment decisions. However, mutations in BRCA1/2, ATRX, and TP53 may guide use of targeted therapies, emphasizing the role of comprehensive molecular profiling in management.

Zenodo (CERN European Organization for Nuclear Research)
Good health and well-being
Openalex Percentile: Top 12%
Sarcoma Diagnosis and Treatment
DOIOpen Access PDFOpenAlex
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What are the common genetic mutations associated with leiomyosarcoma, and how do they influence treatment decisions? — Tripdatabase · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS