Prioritize validation over discovery of novel antibiotics
Cecropin, found in silk moths, was the first antimicrobial peptide isolated from an animal.Today, thousands of AMPs have been characterized, and recent studies have revealed just how important these molecules are for defending against infections.
Authors
- Irene A. Chen (ORCID: https://orcid.org/0000-0001-6040-7927)
- MICHAEL A. ZASLOFF (ORCID: https://orcid.org/0000-0002-1453-9328)
- Thomas C. G. Bosch (ORCID: https://orcid.org/0000-0002-9488-5545)
- Mark A. Hanson (ORCID: https://orcid.org/0000-0002-6125-3672)
Institutions
- Georgetown University (US)
- University of Exeter (GB)
- University of California System (US)
- Christian-Albrechts-Universität zu Kiel (DE)
Publication Details
- Journal
- Proceedings of the National Academy of Sciences
- Published
- 2026-10-28
- DOI
- https://doi.org/10.1073/pnas.2616439123
- Primary Topic
- Microbial Natural Products and Biosynthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Wellcome Trust