Is there a relationship between joint hypermobility and primary lymphedema? A cross-sectional study

J oint hypermobility ( JH) is a clinical condition de- fined by an excessive range of motion in one or more joints beyond normal physiological limits [1].The reported prevalence of JH varies widely, ranging from 0.6% to 31.5%, depending on demographic factors such as race, age, and sex.It is more prevalent in women than in men and shows a progressive decline with advancing age [2,3].Involvement of multiple joints is generally referred to as generalized joint hypermobility (GJH) or joint laxity [4-6].JH represents a spectrum ranging from asymptomatic benign hypermobility to symptomatic hypermobility disorders.The Beighton Scoring System -a widely used 9-point scale for assessing articular hypermobility in adults -has been incorporated into both prior and current diagnostic criteria for hypermobility syndromes [7][8][9][10][11].Despite its recognized limitations [8,9], the scale remains the most widely accepted assessment tool, with a Beighton score of ≥4 commonly applied as the threshold for defining GJH [12][13][14].