Lifetime economic impact of pediatric cataract surgery in sub-Saharan Africa: a case study from Kinshasa
Abstract Childhood cataract is a major cause of treatable childhood blindness in sub-Saharan Africa. Effective care requires case finding, surgery, and long-term follow-up. While economic evaluations largely focus on adult cataract surgery and report high cost-effectiveness, evidence for pediatric cataract care remains limited. We built a lifetime model for bilateral pediatric cataract care, comparing discounted present values of costs and benefits with and without intervention. Costs included case finding, preoperative assessment, bilateral surgery and follow-up; benefits were expressed as age-specific productivity (GDP proxy) and quality-adjusted life years (QALYs). Parameter ranges from local program data, expert input and published sources were tested in one-way and scenario analyses. In the base case, surgery generated a present-value GDP gain of US$23,409 and 5.4 QALYs, indicating cost savings with improved quality of life. The intervention remained cost-saving across most plausible ranges; only an extreme worst-case produced a small negative GDP balance (− US$2,269) while still gaining 1.8 QALYs, remaining strongly cost-effective. Results were driven mainly by the discount rate and post-operative working-age productivity rather than surgical or follow-up costs. High-quality pediatric cataract management can therefore represent a high-return investment, but affordability constraints and uncertainty in long-term outcomes underscore the need for prospective follow-up and financial protection.
Authors
- Janvier Kilangalanga Ngoy (ORCID: https://orcid.org/0000-0002-4863-0824)
- Broder Poschkamp (ORCID: https://orcid.org/0000-0003-2393-0369)
- Hanna Faber (ORCID: https://orcid.org/0000-0002-7864-7264)
- Adrian Hopkins (ORCID: https://orcid.org/0000-0002-3367-3231)
- Steffen Fleßa
- Ellen Steinau
- Rudolf Friedrich Guthoff
- Andreas Stahl
Institutions
- Universitätsmedizin Greifswald (DE)
- Universität Greifswald (DE)
- Université Catholique du Graben (CD)
- University Medical Center Hamburg-Eppendorf (DE)
- Universitätsmedizin Rostock (DE)
Publication Details
- Journal
- Scientific Reports
- Published
- 2026-10-28
- DOI
- https://doi.org/10.1038/s41598-026-72558-z
- Primary Topic
- Health Systems, Economic Evaluations, Quality of Life
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Johns Hopkins University
- Deutsche Forschungsgemeinschaft
- Christoffel Blinden Mission
- Else Kröner-Fresenius-Stiftung
- Universität Rostock