How does the combination of pramipexole and olanzapine affect the management of treatment-resistant depression compared to other drug combinations?

No direct evidence for the combination of pramipexole and olanzapine in treatment-resistant depression was identified. Indirect data suggest both drugs individually show promise for augmentation, but their combined efficacy and safety compared to other drug combinations remain untested.

Authors

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-10-28
DOI
https://doi.org/10.5281/zenodo.23722296
Primary Topic
Treatment of Major Depression
Type
article
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article

How does the combination of pramipexole and olanzapine affect the management of treatment-resistant depression compared to other drug combinations?

Tripdatabase
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Zenodo (CERN European Organization for Nuclear Research)
Treatment of Major Depression
article

How does the combination of pramipexole and olanzapine affect the management of treatment-resistant depression compared to other drug combinations?

Tripdatabase
article en

Abstract

No direct evidence for the combination of pramipexole and olanzapine in treatment-resistant depression was identified. Indirect data suggest both drugs individually show promise for augmentation, but their combined efficacy and safety compared to other drug combinations remain untested.

Zenodo (CERN European Organization for Nuclear Research)
Good health and well-being
Openalex Percentile: Top 13%
Treatment of Major Depression
DOIOpen Access PDFOpenAlex
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How does the combination of pramipexole and olanzapine affect the management of treatment-resistant depression compared to other drug combinations? — Tripdatabase · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS