Prevalence and association of severity of BHP among COPD Patients: a cross sectional study

Background: Benign prostatic hyperplasia (BPH) is a common condition in ageing men, causing lower urinary tract symptoms and bladder outlet obstruction. Chronic obstructive pulmonary disease (COPD) is a systemic inflammatory disorder with significant extrapulmonary effects. The coexistence of BPH and COPD may worsen urinary dysfunction due to impaired detrusor activity and hypoxia. This combination increases the risk of obstructive uropathy and related complications, highlighting an important clinical concern requiring further evaluation Objectives: To determine prevalence and association of severity of BPH among COPD patients and assess association with disease severity. Methods: This cross-sectional study was conducted at Dhaka National Medical College and Institute Hospital, Dhaka, from January to December 2025 among 152 COPD patients with lower urinary tract symptoms. Data were collected using questionnaires, clinical examination, and investigations including ultrasonography and IPSS scoring. Patients meeting inclusion criteria were enrolled. Statistical analysis was performed using SPSS version 25, applying descriptive and inferential methods, with significance considered at p < 0.05. Ethical approval and informed consent were obtained. Result: Among 152 male COPD patients with lower urinary tract symptoms, the mean age was 61.2±9.4 years, and 84.2% had coexisting BPH (moderate severity 54.7%). PVR >100 mL was seen in 88.2%, hydronephrosis in 44.1%, elevated creatinine in 46.7%, and recurrent UTIs in 35.5%. BPH prevalence increased from 66.7% (GOLD 1) to 94.7% (GOLD 4). Nocturia (87.5%), weak stream (81.3%), and urgency (76.6%) were common. Alpha-blocker use was 76.6%; Quality of life was “terrible” in 55.3%. Severe BPH correlated with worse outcomes (p<0.05). Conclusion: BPH is highly prevalent among COPD patients, causing significant complications and reduced quality of life, emphasizing need for early diagnosis and management. J Dhaka National Med. Coll. Hos. 2026; 32 (02): 21-26

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Journal
Journal of Dhaka National Medical College & Hospital
Published
2026-10-28
DOI
https://doi.org/10.3329/jdnmch.v32i2.94221
Primary Topic
Urinary Bladder and Prostate Research
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article
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article

Prevalence and association of severity of BHP among COPD Patients: a cross sectional study

Md Shahen, Farhana Akter, Mohammed Asaduzzaman Khan, Md Afzal Hossain et al.
Journal of Dhaka National Medical College & Hospital
Urinary Bladder and Prostate Research
article

Prevalence and association of severity of BHP among COPD Patients: a cross sectional study

Md Shahen, Farhana Akter, Mohammed Asaduzzaman Khan, Md Afzal Hossain, Mohammad Shafiqul Islam
article en

Abstract

Background: Benign prostatic hyperplasia (BPH) is a common condition in ageing men, causing lower urinary tract symptoms and bladder outlet obstruction. Chronic obstructive pulmonary disease (COPD) is a systemic inflammatory disorder with significant extrapulmonary effects. The coexistence of BPH and COPD may worsen urinary dysfunction due to impaired detrusor activity and hypoxia. This combination increases the risk of obstructive uropathy and related complications, highlighting an important clinical concern requiring further evaluation Objectives: To determine prevalence and association of severity of BPH among COPD patients and assess association with disease severity. Methods: This cross-sectional study was conducted at Dhaka National Medical College and Institute Hospital, Dhaka, from January to December 2025 among 152 COPD patients with lower urinary tract symptoms. Data were collected using questionnaires, clinical examination, and investigations including ultrasonography and IPSS scoring. Patients meeting inclusion criteria were enrolled. Statistical analysis was performed using SPSS version 25, applying descriptive and inferential methods, with significance considered at p < 0.05. Ethical approval and informed consent were obtained. Result: Among 152 male COPD patients with lower urinary tract symptoms, the mean age was 61.2±9.4 years, and 84.2% had coexisting BPH (moderate severity 54.7%). PVR >100 mL was seen in 88.2%, hydronephrosis in 44.1%, elevated creatinine in 46.7%, and recurrent UTIs in 35.5%. BPH prevalence increased from 66.7% (GOLD 1) to 94.7% (GOLD 4). Nocturia (87.5%), weak stream (81.3%), and urgency (76.6%) were common. Alpha-blocker use was 76.6%; Quality of life was “terrible” in 55.3%. Severe BPH correlated with worse outcomes (p<0.05). Conclusion: BPH is highly prevalent among COPD patients, causing significant complications and reduced quality of life, emphasizing need for early diagnosis and management. J Dhaka National Med. Coll. Hos. 2026; 32 (02): 21-26

Journal of Dhaka National Medical College & HospitalVol. 32(2)
Communications Consortium Media Center (US), Dhaka National Medical College (BD), Dhaka Medical College and Hospital (BD)
Good health and well-being
Openalex Percentile: Top 10%
Urinary Bladder and Prostate Research
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