Tumor growth models with nutrient consumption

We study the saturation free boundary of the cell density and its interaction with the nutrient depletion interface in a coupled parabolic model for tumor growth with sublinear reactions. We establish a sharp quadratic--superquadratic growth dichotomy along the saturation interface and quantify the degeneration of quadratic profiles as they approach the joint saturation--depletion boundary. We further show that intrinsic regularity of the saturation interface can occur only at joint free boundary points, where half-space blow-ups of either component determine a unique joint blow-up profile. Finally, we prove a local backward coincidence between the joint and nutrient free boundaries near regular points, which yields spatial and temporal regularity of the joint interface.

Authors

Publication Details

Journal
arXiv (Cornell University)
Published
2026-10-27
DOI
https://doi.org/10.48550/arxiv.2610.37144
Primary Topic
Mathematical Biology Tumor Growth
Type
preprint
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preprint

Tumor growth models with nutrient consumption

Rafayel Teymurazyan, Damião J. Araújo, José Miguel Urbano
arXiv (Cornell University)
Mathematical Biology Tumor Growth
preprint

Tumor growth models with nutrient consumption

Rafayel Teymurazyan, Damião J. Araújo, José Miguel Urbano
preprint en

Abstract

We study the saturation free boundary of the cell density and its interaction with the nutrient depletion interface in a coupled parabolic model for tumor growth with sublinear reactions. We establish a sharp quadratic--superquadratic growth dichotomy along the saturation interface and quantify the degeneration of quadratic profiles as they approach the joint saturation--depletion boundary. We further show that intrinsic regularity of the saturation interface can occur only at joint free boundary points, where half-space blow-ups of either component determine a unique joint blow-up profile. Finally, we prove a local backward coincidence between the joint and nutrient free boundaries near regular points, which yields spatial and temporal regularity of the joint interface.

arXiv (Cornell University)
Mathematical Biology Tumor Growth
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