Post Acute Sequelae of COVID 19: A Prospective Observational Study

The aim was to evaluate sequelae of COVID-19 on CXR and HRCT thorax in young and middle-aged patients. This was a prospective observational study comprising a total number of 58 COVID cases from November 2020 to October 2022. The baseline scan during the active phase of the disease was collected followed by CT scan done 3 to 24 months later. 30 patients had mild disease, 15 had moderate and 13 had severe disease during the active phase of the disease (based on CT severity score - out of 25). 39.66% patients showed post- acute-infection sequelae of COVID. Fibrosis was the predominant sequelae observed in 21 patients- mild in10, moderate in 9 and severe in 2. Fibrosis was more common with advancing age in the age group of 41-50 years (61% had fibrosis). The majority of the patients (60%) showed complete clearance of the acute changes in the lung. Post COVID lung fibrosis was found approximately in 36 % of patients, predominantly in patients with moderate to severe disease.

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Publication Details

Journal
International Journal of Science and Research (IJSR)
Published
2026-10-28
DOI
https://doi.org/10.21275/sr261025165256
Primary Topic
Long-Term Effects of COVID-19
Type
article
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article

Post Acute Sequelae of COVID 19: A Prospective Observational Study

Shishir Chumber, Kavita Vani, Ibne Ahmad, Arfi Aara et al.
International Journal of Science and Research (IJSR)
Long-Term Effects of COVID-19
article

Post Acute Sequelae of COVID 19: A Prospective Observational Study

Shishir Chumber, Kavita Vani, Ibne Ahmad, Arfi Aara, Mehtab Ahmed
article en

Abstract

The aim was to evaluate sequelae of COVID-19 on CXR and HRCT thorax in young and middle-aged patients. This was a prospective observational study comprising a total number of 58 COVID cases from November 2020 to October 2022. The baseline scan during the active phase of the disease was collected followed by CT scan done 3 to 24 months later. 30 patients had mild disease, 15 had moderate and 13 had severe disease during the active phase of the disease (based on CT severity score - out of 25). 39.66% patients showed post- acute-infection sequelae of COVID. Fibrosis was the predominant sequelae observed in 21 patients- mild in10, moderate in 9 and severe in 2. Fibrosis was more common with advancing age in the age group of 41-50 years (61% had fibrosis). The majority of the patients (60%) showed complete clearance of the acute changes in the lung. Post COVID lung fibrosis was found approximately in 36 % of patients, predominantly in patients with moderate to severe disease.

International Journal of Science and Research (IJSR)
Vardhman Mahavir Medical College & Safdarjung Hospital (IN), Vinayaka Missions Medical College and Hospitals (IN)
Good health and well-being
Openalex Percentile: Top 14%
Long-Term Effects of COVID-19
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Post Acute Sequelae of COVID 19: A Prospective Observational Study — Shishir Chumber, Kavita Vani, et al. · International Journal of Science and Research (IJSR) (2026) | TGRS Research Map | TGRS