Exclusive lingual psoriasis revealed by dermoscopy

Psoriasis is a chronic immune-mediated disease, in which oral involvement is uncommon and frequently overlooked.We report a 38-year-old man with no personal or family history of psoriasis who presented with chronic, recurrent erythematous depapillation of the left hemi-tongue, and unresponsive to prolonged antifungal therapy.Dermoscopy showed regularly distributed dotted vessels over hypertrophic papillae, contrasting with the normal contralateral mucosa, and guided a targeted punch biopsy.Histology demonstrated psoriasiform epithelial hyperplasia with parakeratosis, elongated rete ridges, and dilated tortuous capillaries within the lamina propria and Munro microabscesses; periodic acid-Schiff staining excluded fungal infection.Extension work-up disclosed no cutaneous, scalp, nail, or joint involvement, supporting exclusive lingual psoriasis.Topical clobetasol propionate produced marked improvement within 4 weeks, with no relapse after 1 year of follow-up.This case illustrates the value of dermoscopy in recognizing atypical oral psoriasis and in avoiding prolonged ineffective antifungal treatment.

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Publication Details

Journal
Portuguese Journal of Dermatology and Venereology
Published
2026-10-28
DOI
https://doi.org/10.24875/pjdv.26000094
Primary Topic
Psoriasis: Treatment and Pathogenesis
Type
article
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article

Exclusive lingual psoriasis revealed by dermoscopy

Meryem Soughi, Oumaima Zouine, Aimane Zaim, Fatima Zahrae-Mernissi
Portuguese Journal of Dermatology and Venereology
Psoriasis: Treatment and Pathogenesis
article

Exclusive lingual psoriasis revealed by dermoscopy

Meryem Soughi, Oumaima Zouine, Aimane Zaim, Fatima Zahrae-Mernissi
article en

Abstract

Psoriasis is a chronic immune-mediated disease, in which oral involvement is uncommon and frequently overlooked.We report a 38-year-old man with no personal or family history of psoriasis who presented with chronic, recurrent erythematous depapillation of the left hemi-tongue, and unresponsive to prolonged antifungal therapy.Dermoscopy showed regularly distributed dotted vessels over hypertrophic papillae, contrasting with the normal contralateral mucosa, and guided a targeted punch biopsy.Histology demonstrated psoriasiform epithelial hyperplasia with parakeratosis, elongated rete ridges, and dilated tortuous capillaries within the lamina propria and Munro microabscesses; periodic acid-Schiff staining excluded fungal infection.Extension work-up disclosed no cutaneous, scalp, nail, or joint involvement, supporting exclusive lingual psoriasis.Topical clobetasol propionate produced marked improvement within 4 weeks, with no relapse after 1 year of follow-up.This case illustrates the value of dermoscopy in recognizing atypical oral psoriasis and in avoiding prolonged ineffective antifungal treatment.

Portuguese Journal of Dermatology and Venereology
Centre Hospitalier Universitaire Hassan II (MA), Sidi Mohamed Ben Abdellah University (MA)
Good health and well-being
Openalex Percentile: Top 19%
Psoriasis: Treatment and Pathogenesis
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Exclusive lingual psoriasis revealed by dermoscopy — Meryem Soughi, Oumaima Zouine, et al. · Portuguese Journal of Dermatology and Venereology (2026) | TGRS Research Map | TGRS