Pyogenic granuloma. A case report

Background: Pyogenic granuloma, also known as lobular capillary hemangioma, is a common benign vascular proliferation of the skin and mucous membranes characterized by rapid growth and a tendency to bleed following minor trauma. Although its clinical appearance is often characteristic, it may mimic other vascular or malignant lesions, making histopathological examination important for establishing the diagnosis. We present the case of a 43-year-old woman with no relevant medical history who developed a rapidly growing, bleeding lesion on the third finger of the left hand over a 6-week period. Physical examination revealed a solitary, semispherical, lobulated, sessile, reddish-violet nodule measuring approximately 1 × 1 cm, with a granulation tissue-like appearance and a soft consistency. Complete surgical excision was performed, followed by direct closure of the surgical defect, and the specimen was submitted for histopathological examination. Histopathological evaluation demonstrated a dermal vascular proliferation composed of numerous small-caliber capillaries lined by prominent endothelial cells and arranged in a characteristic lobular pattern, separated by edematous stroma. A mixed inflammatory infiltrate and extravasated erythrocytes were also identified. These findings established the diagnosis of pyogenic granuloma (lobular capillary hemangioma). Surgical excision with primary closure provides both definitive treatment and tissue for histopathological confirmation and is associated with a low recurrence rate. Recognition of its clinical and histopathological features is essential to differentiate pyogenic granuloma from other benign and malignant lesions with similar presentations. Keywords: Granuloma, Pyogenic; Hemangioma, Capillary; Recurrence.