Neurolisteriosis with a stroke-like presentation in a male adult with polymyalgia rheumatica: a case report and literature review

Listeria monocytogenes is a gram-positive bacillus that can cause a wide spectrum of clinical manifestations, ranging from paucisymptomatic to life-threatening disease. Central nervous system involvement is called neurolisteriosis and is a rare and severe entity that includes meningitis, meningoencephalitis, rhombencefalitis, and brain abscess, and it may start with a stroke-like presentation. People with rheumatic diseases taking immunosuppressive medications are at increased risk, and they also can have atypical presentations, misleading the diagnosis of infection. Magnetic resonance imaging can guide the diagnosis; however, a high clinical suspicion and a microbiological confirmation are needed. Here we present a case of Listeria monocytogenes brain abscess mimicking an ischemic stroke that occurred in a male patient with a previous diagnosis of polymyalgia rheumatica under immunosuppressive treatment. A literature revision was also performed.

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Publication Details

Journal
Italian Journal of Medicine
Published
2026-10-27
DOI
https://doi.org/10.4081/itjm.2026.2619
Primary Topic
Infectious Diseases and Tuberculosis
Type
article
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article

Neurolisteriosis with a stroke-like presentation in a male adult with polymyalgia rheumatica: a case report and literature review

Salvatore Di Bartolomeo, Francesco Carubbi, Serena Pasquarelli, Ester Liberatore et al.
Italian Journal of Medicine
Infectious Diseases and Tuberculosis
article

Neurolisteriosis with a stroke-like presentation in a male adult with polymyalgia rheumatica: a case report and literature review

Salvatore Di Bartolomeo, Francesco Carubbi, Serena Pasquarelli, Ester Liberatore, FLAVIO ROMOLO RISPOLI, Luigi Evandro Aloisantonio, Piero Francesco Agrippino
article en

Abstract

Listeria monocytogenes is a gram-positive bacillus that can cause a wide spectrum of clinical manifestations, ranging from paucisymptomatic to life-threatening disease. Central nervous system involvement is called neurolisteriosis and is a rare and severe entity that includes meningitis, meningoencephalitis, rhombencefalitis, and brain abscess, and it may start with a stroke-like presentation. People with rheumatic diseases taking immunosuppressive medications are at increased risk, and they also can have atypical presentations, misleading the diagnosis of infection. Magnetic resonance imaging can guide the diagnosis; however, a high clinical suspicion and a microbiological confirmation are needed. Here we present a case of Listeria monocytogenes brain abscess mimicking an ischemic stroke that occurred in a male patient with a previous diagnosis of polymyalgia rheumatica under immunosuppressive treatment. A literature revision was also performed.

Italian Journal of Medicine
University of L'Aquila (IT), San Salvatore Hospital (IT)
Good health and well-being
Openalex Percentile: Top 10%
Infectious Diseases and Tuberculosis
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Neurolisteriosis with a stroke-like presentation in a male adult with polymyalgia rheumatica: a case report and literature review — Salvatore Di Bartolomeo, Francesco Carubbi, et al. · Italian Journal of Medicine (2026) | TGRS Research Map | TGRS