Anaesthetic Considerations for Twin Delivery in a Patient With Osteogenesis Imperfecta Type III: A Case Report

Osteogenesis imperfecta is an uncommon, inherited connective tissue disease, which is rare in pregnancy and presents multiple challenges to perinatal and anaesthetic care.Caesarean section in these patients is complex, often performed preterm and demands careful coordination between multiple disciplines.A 27year-old woman at 26 weeks' gestation of a spontaneous twin pregnancy presented for elective caesarean section for worsening respiratory failure.General anaesthesia with total intravenous anaesthesia was used in view of anticipated prolonged surgery and difficult regional anaesthesia.The delivery was largely uneventful, and the patient recovered without major complications.The twins experienced multiple complications of prematurity.This case highlights the importance of multidisciplinary planning in achieving favourable maternal and foetal outcomes in high-risk pregnancies.

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Publication Details

Journal
Cureus
Published
2026-10-27
DOI
https://doi.org/10.7759/cureus.118667
Primary Topic
Anesthesia and Pain Management
Type
article
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0.00
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article

Anaesthetic Considerations for Twin Delivery in a Patient With Osteogenesis Imperfecta Type III: A Case Report

Leonard Wei Wen Loh, Sneha E Eapen, Bronte Bang Ting Jong
Cureus
Anesthesia and Pain Management
article

Anaesthetic Considerations for Twin Delivery in a Patient With Osteogenesis Imperfecta Type III: A Case Report

Leonard Wei Wen Loh, Sneha E Eapen, Bronte Bang Ting Jong
article en

Abstract

Osteogenesis imperfecta is an uncommon, inherited connective tissue disease, which is rare in pregnancy and presents multiple challenges to perinatal and anaesthetic care.Caesarean section in these patients is complex, often performed preterm and demands careful coordination between multiple disciplines.A 27year-old woman at 26 weeks' gestation of a spontaneous twin pregnancy presented for elective caesarean section for worsening respiratory failure.General anaesthesia with total intravenous anaesthesia was used in view of anticipated prolonged surgery and difficult regional anaesthesia.The delivery was largely uneventful, and the patient recovered without major complications.The twins experienced multiple complications of prematurity.This case highlights the importance of multidisciplinary planning in achieving favourable maternal and foetal outcomes in high-risk pregnancies.

Cureus
Singapore General Hospital (SG)
Good health and well-being
Openalex Percentile: Top 10%
Anesthesia and Pain Management
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